We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Primary Aldosteronism Due to Adrenal Hyperplasia:  Occurrence in a Boy Aged 10 Years

AMA Am J Dis Child. 1959;98(1):90-99. doi:10.1001/archpedi.1959.02070020092012.
Text Size: A A A
Published online

Since Conn's description of the clinical features associated with primary aldosteronism in 1955,1 several other cases have been reported in the literature.2-12 This syndrome, which is the result of hypersecretion by the adrenal gland of the mineralocorticoid hormone aldosterone, is usually due to a functioning adrenocortical adenoma. In the few cases without adenoma, hyperplasia chiefly involving the zona fasciculata has been found,9 and hyperaldosteronism due to adrenocortical carcinoma with hepatic metastases has been reported.4 All patients were adults except one girl 6 aged 13, and one boy 12 aged 9 years.

The clinical syndrome originally described by Conn 1,13 consists essentially of polyuria and polydipsia, arterial hypertension, periodic weakness and "paralyses," paresthesiae, and intermittent tetany. These findings are associated with altered electrolyte metabo

lism manifested by metabolic alkalosis with hypokalemia and hypernatremia, and elevated potassium content of sweat, saliva, and urine, with low sweat, salivary, and


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.