0
March 1959, Vol 97, No. 3 >
Article | March 1959

Subclinical Pneumocystis Pneumonitis FREE

WALTER H. SHELDON, M.D.
[+] Author Affiliations

Submitted for publication July 8, 1958.

Aided by Grant No. 71 from the Playtex Park Research Institute.


AMA Am J Dis Child. 1959;97(3):287-297. doi:10.1001/archpedi.1959.02070010289005.
Text Size: A A A
Published online
Article
References
Comments

In Europe, Pneumocystis carinii or interstitial plasma-cell pneumonia is frequent; it affects chiefly premature or otherwise debilitated infants, and it occurs sometimes in small epidemics.1 The highest incidence of the infection is at the age of 4 weeks to 6 months. The mortality is high and is not influenced by therapy. The typical autopsy findings show an extensive pneumonia characterized by plasma-cell infiltration of the alveolar septa and a peculiar intraalveolar material with many minute organisms. These have been identified as P. carinii and are generally accepted as the causative agent, although they have not been isolated in culture. Unequivocal transsion of the infection to experimental animals has not been accomplished. There is much controversy regarding the taxonomic position of the organism, which some consider a protozoon, others, a fungus.

In North America, Pneumocystic pneumonia is thought to be a rare disorder and thus far only a few isolated

REFERENCES

1 +
Gajdusek, D. C.:  Pneumocystis Carinii: Etiologic Agent of Plasma Cell Pneumonia of Premature and Young Infants , Pediatrics 19:543, 1957;.
2 +
Danzier, G.; Thayer, W., and Barnett, R. N.:  Pneumocystis Carinii Pneumonia in an Infant , Am. J. Clin. Path. 26:787, 1956;.
3 +
Russell, H. T., and Nelson, B. M.:  Pneumocystis Pneumonitis in American Infants , Am. J. Clin. Path. 26:1334, 1956;.
4 +
Gagne, F., and Hould, F.:  Interstitial Plasma Cellular (Parasitic) Pneumonia in Infants , Canad. M. A. J. 74:620, 1956;.
5 +
Gerrard, J. W., and Moore, D. F.:  Interstitial Plasma Cellular Pneumonia Due to Pneumocystis Carinii , Canad. M. A. J. 76:299, 1957;.
6 +
Howard, R. M., and Sheldon, W. H.:  Pneumocystis Pneumonia , A. M. A. J. Dis. Child. 95: 18, 1958;.
7 +
Eberling, E. W., and Cohen, F.:  Pneumocystis Carinii Pneumonia , Pediatrics 21:345, 1958;.
8 +
Lunseth, J. H.; Kirmse, T. W.; Prezyna, A. P., and Gerth, R. E.:  Interstitial Plasma Cell Pneumonia , J. Pediat. 46:137, 1955;.
9 +
Donohue, W. L.:  Interstitial Plasma Cell Pneumonia , J. Lab. Invest. 5:97, 1956;.
10 +
Klein, H.:  Die interstitielle plasmacelluläre Pneumonie als Todesursache im Säuglings- und frühen Kindesalter , Deutsche Ztschr. ges. gericht. Med. 44:262, 1955;.
11 +
Bachmann, K. D.:  Plötzlicher Tod durch frühkindliche interstitielle plasmazelluläre Pneumonie , Deutsche Ztschr. ges. gericht. Med. 44:362, 1955;.
12 +
Jírovec, O., and Vaněk, J.:  Zur Morphologie der Pneumocystis carinii und zur Pathogenese der Pneumocystis-Pneumonie , Zentralbl. allg. Path. 92:424, 1954;.
13 +
Hamperl, H.:  Variants of Pneumocystis Pneumonia , J. Path. & Bact. 84:353, 1957;.
14 +
Hamperl, H.:  Über heilende und abortive Pneumocystis-Pneumonie , Arch. path. Anat. 330: 325, 1957;.
15 +
Liebow, A. A.: Personal communication to the author.
16 +
Sheldon, W. H.: Unpublished data.
17 +
Sedlmeier, H., and Dahme, E.:  Pneumocystis Carinii: Infektion beim Hund , Zentralbl. allg. Path. 93:150, 1955;.
18 +
Van der Meer, G., and Brug, S. L.:  Infection à Pneumocystis chez l'homme et chez les animaux , Ann. Soc. belge de med. trop. 22:301, 1942;.
19 +
Weisse, K., and Wedler, E.:  Über das Vorkommen der sogenannten "Pneumocystis Carinii," Klin. Wchnschr. 32:270, 1954;.
20 +
Le Tan Vinh:  La pneumonie à Pneumocystis: Ses Rapports avec la pneumonie interstitielle à plasmocytes , Arch. franç. pédiat. 11:1035, 1954;.
21 +
Hamperl, H.:  Pneumocystis Infection and Cytomegaly of the Lungs in the Newborn and Adult , Am. J. Path. 32:1, 1956;.
22 +
Wyatt, J. P.; Simon, T.; Trumbull, M. L., and Evans, M.:  Cytomegalic Inclusion Pneumonitis in the Adult , Am. J. Clin. Path. 23:353, 1953;.
23 +
Orlandini, T. O.; Sass-Kortsak, A., and Ebbs, J. H.:  Serum Gamma Globulin Levels in Normal Infants , Pediatrics 16:575, 1955;.
24 +
Hutchinson, J. H.:  Congenital Agammaglobulinæmia , Lancet 2:844; 1196, 1955;.
25 +
Bird, T., and Thompson, J.:  "Pneumocystis Carinii" Pneumonia , Lancet 1:59, 1957;.
26 +
Good, R. A., and Zak, S. J.:  Disturbances in Gamma Globulin Synthesis as "Experiments of Nature," Pediatrics 18:109, 1956;.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Gajdusek, D. C.:  Pneumocystis Carinii: Etiologic Agent of Plasma Cell Pneumonia of Premature and Young Infants , Pediatrics 19:543, 1957;.
2 +
Danzier, G.; Thayer, W., and Barnett, R. N.:  Pneumocystis Carinii Pneumonia in an Infant , Am. J. Clin. Path. 26:787, 1956;.
3 +
Russell, H. T., and Nelson, B. M.:  Pneumocystis Pneumonitis in American Infants , Am. J. Clin. Path. 26:1334, 1956;.
4 +
Gagne, F., and Hould, F.:  Interstitial Plasma Cellular (Parasitic) Pneumonia in Infants , Canad. M. A. J. 74:620, 1956;.
5 +
Gerrard, J. W., and Moore, D. F.:  Interstitial Plasma Cellular Pneumonia Due to Pneumocystis Carinii , Canad. M. A. J. 76:299, 1957;.
6 +
Howard, R. M., and Sheldon, W. H.:  Pneumocystis Pneumonia , A. M. A. J. Dis. Child. 95: 18, 1958;.
7 +
Eberling, E. W., and Cohen, F.:  Pneumocystis Carinii Pneumonia , Pediatrics 21:345, 1958;.
8 +
Lunseth, J. H.; Kirmse, T. W.; Prezyna, A. P., and Gerth, R. E.:  Interstitial Plasma Cell Pneumonia , J. Pediat. 46:137, 1955;.
9 +
Donohue, W. L.:  Interstitial Plasma Cell Pneumonia , J. Lab. Invest. 5:97, 1956;.
10 +
Klein, H.:  Die interstitielle plasmacelluläre Pneumonie als Todesursache im Säuglings- und frühen Kindesalter , Deutsche Ztschr. ges. gericht. Med. 44:262, 1955;.
11 +
Bachmann, K. D.:  Plötzlicher Tod durch frühkindliche interstitielle plasmazelluläre Pneumonie , Deutsche Ztschr. ges. gericht. Med. 44:362, 1955;.
12 +
Jírovec, O., and Vaněk, J.:  Zur Morphologie der Pneumocystis carinii und zur Pathogenese der Pneumocystis-Pneumonie , Zentralbl. allg. Path. 92:424, 1954;.
13 +
Hamperl, H.:  Variants of Pneumocystis Pneumonia , J. Path. & Bact. 84:353, 1957;.
14 +
Hamperl, H.:  Über heilende und abortive Pneumocystis-Pneumonie , Arch. path. Anat. 330: 325, 1957;.
15 +
Liebow, A. A.: Personal communication to the author.
16 +
Sheldon, W. H.: Unpublished data.
17 +
Sedlmeier, H., and Dahme, E.:  Pneumocystis Carinii: Infektion beim Hund , Zentralbl. allg. Path. 93:150, 1955;.
18 +
Van der Meer, G., and Brug, S. L.:  Infection à Pneumocystis chez l'homme et chez les animaux , Ann. Soc. belge de med. trop. 22:301, 1942;.
19 +
Weisse, K., and Wedler, E.:  Über das Vorkommen der sogenannten "Pneumocystis Carinii," Klin. Wchnschr. 32:270, 1954;.
20 +
Le Tan Vinh:  La pneumonie à Pneumocystis: Ses Rapports avec la pneumonie interstitielle à plasmocytes , Arch. franç. pédiat. 11:1035, 1954;.
21 +
Hamperl, H.:  Pneumocystis Infection and Cytomegaly of the Lungs in the Newborn and Adult , Am. J. Path. 32:1, 1956;.
22 +
Wyatt, J. P.; Simon, T.; Trumbull, M. L., and Evans, M.:  Cytomegalic Inclusion Pneumonitis in the Adult , Am. J. Clin. Path. 23:353, 1953;.
23 +
Orlandini, T. O.; Sass-Kortsak, A., and Ebbs, J. H.:  Serum Gamma Globulin Levels in Normal Infants , Pediatrics 16:575, 1955;.
24 +
Hutchinson, J. H.:  Congenital Agammaglobulinæmia , Lancet 2:844; 1196, 1955;.
25 +
Bird, T., and Thompson, J.:  "Pneumocystis Carinii" Pneumonia , Lancet 1:59, 1957;.
26 +
Good, R. A., and Zak, S. J.:  Disturbances in Gamma Globulin Synthesis as "Experiments of Nature," Pediatrics 18:109, 1956;.

Correspondence

Submit a Letter
CME
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Clear Answers | Save For Later
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Compression-Only CPR: Pushing the Science Forward
Cone
AAM 2010;304:1493-1495.
All you need to read in the other general journals
BMJ 2010;341:c5893-c1494.
Submit a Comment

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

© 2013 American Medical Association. All Rights Reserved.
Powered bySilverchair Information Systems