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Acute Ataxia of Childhood: A Summary of Fifteen Cases FREE

GENE M. LASATER, M.D.; J. T. JABBOUR, M.D.
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Submitted for publication April 14, 1958.


AMA Am J Dis Child. 1959;97(1):61-65. doi:10.1001/archpedi.1959.02070010063004.
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Ataxia is a symptom commonly encountered in children. From a therapeutic and prognostic standpoint, ataxia produced by posterior fossa tumors and spinocerebellar degeneration must be differentiated from that which is symptomatic of a more benign self-limited disease. Shanks1 observed that a poor prognosis was usually associated with ataxia of insidious and chronic onset. On the other hand, spontaneous recovery usually occurred in children in whom ataxia had developed acutely. This condition has been referred to as "acute cerebellar ataxia." It is generally a benign disorder, subsiding in a few days or weeks. Adults are only rarely affected. The etiology is often undetermined, but in most cases it is thought to be a cerebellar encephalitis of infectious or toxic origin. The following is a summary of the clinical picture and a discussion of possible etiologies based on reports in the literature and our own observations of 15 cases.

Clinical Picture 

REFERENCES

Shanks, R. A.:  Notes on Cerebellar Ataxia in Childhood , Arch. Dis. Childhood 25:389, 1950;.
Griffith, J. P. C.:  Acute Cerebellar Encephalitis , Am. J. M. Sc. 162:781, 1921;.
Batten, F. E.:  Ataxia in Childhood , Brain 28: 484, 1905;.
Klingman, W. O., and Hodges, R. G.:  Acute Ataxia of Unknown Origin in Children , J. Pediat. 24:536, 1944;.
Goldwyn, A., and Waldman, A. M.:  Acute Cerebellar Ataxia in Children , J. Pediat. 42:75, 1953;.
Cottom, D. G.:  Acute Cerebellar Ataxia , Arch. Dis. Childhood 32:181, 1957;.
Underwood, E. A.:  The Neurological Complications of Varicella , Brit. J. Child. Dis. 32:83, 1935;.
Galli, P.:  Nervous Complications of Varicella , Pediatria 33:681, 1925;.
J. A. M. A. 85:781, 1925;.
Tyler, H. R.:  Neurological Complications of Rubeola , Medicine 36:147, 1957;.
Ford, F. R.: Diseases of the Nervous System in Infancy, Childhood and Adolescence , Springfield, Ill., Charles C Thomas, 1952;, p. 620 and p. 661.
Baker, A. B.:  The Central Nervous System in Infectious Diseases of Childhood , Postgrad. Med. 5:1, 1949;.
Holub, V.:  Mumps Cerebellitis Without Parotitis but Proved Serologically , Unitr. lek. Brno. 1:127, 1955;.
Rydenstam, B.:  Some Atypical Cases of Poliomyelitis , Acta med. scandinav. , (Supp.) 316:50, 1956;.
Berglund, G.; Mossberg, H. O., and Rydenstam, B.:  Acute Cerebellar Ataxia in Children , Acta Pædiat . 44:254, 1955;.
Friedman, J. H., and Cancellieri, R.:  Central Nervous System Complications of Asian Influenza , New York J. Med. 58:859, 1958;.
Hoyne, R. M.:  Involvement of the Central Nervous System in Infectious Mononucleosis , Arch. Neurol. & Psychiat. 63:606, 1950;.
Bing, R. J.; McNamara, B., and Hopkins, F. H.:  Studies on the Pharmacology of DDT , Bull. Johns Hopkins Hosp. 78:308, 1946;.
Onifer, T. M., and Whisnant, J. P.:  Cerebellar Ataxia and Neuronitis After Exposure to DDT and Lindane , Proc. Staff Meet. Mayo Clin. 32:67, 1957;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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References

Shanks, R. A.:  Notes on Cerebellar Ataxia in Childhood , Arch. Dis. Childhood 25:389, 1950;.
Griffith, J. P. C.:  Acute Cerebellar Encephalitis , Am. J. M. Sc. 162:781, 1921;.
Batten, F. E.:  Ataxia in Childhood , Brain 28: 484, 1905;.
Klingman, W. O., and Hodges, R. G.:  Acute Ataxia of Unknown Origin in Children , J. Pediat. 24:536, 1944;.
Goldwyn, A., and Waldman, A. M.:  Acute Cerebellar Ataxia in Children , J. Pediat. 42:75, 1953;.
Cottom, D. G.:  Acute Cerebellar Ataxia , Arch. Dis. Childhood 32:181, 1957;.
Underwood, E. A.:  The Neurological Complications of Varicella , Brit. J. Child. Dis. 32:83, 1935;.
Galli, P.:  Nervous Complications of Varicella , Pediatria 33:681, 1925;.
J. A. M. A. 85:781, 1925;.
Tyler, H. R.:  Neurological Complications of Rubeola , Medicine 36:147, 1957;.
Ford, F. R.: Diseases of the Nervous System in Infancy, Childhood and Adolescence , Springfield, Ill., Charles C Thomas, 1952;, p. 620 and p. 661.
Baker, A. B.:  The Central Nervous System in Infectious Diseases of Childhood , Postgrad. Med. 5:1, 1949;.
Holub, V.:  Mumps Cerebellitis Without Parotitis but Proved Serologically , Unitr. lek. Brno. 1:127, 1955;.
Rydenstam, B.:  Some Atypical Cases of Poliomyelitis , Acta med. scandinav. , (Supp.) 316:50, 1956;.
Berglund, G.; Mossberg, H. O., and Rydenstam, B.:  Acute Cerebellar Ataxia in Children , Acta Pædiat . 44:254, 1955;.
Friedman, J. H., and Cancellieri, R.:  Central Nervous System Complications of Asian Influenza , New York J. Med. 58:859, 1958;.
Hoyne, R. M.:  Involvement of the Central Nervous System in Infectious Mononucleosis , Arch. Neurol. & Psychiat. 63:606, 1950;.
Bing, R. J.; McNamara, B., and Hopkins, F. H.:  Studies on the Pharmacology of DDT , Bull. Johns Hopkins Hosp. 78:308, 1946;.
Onifer, T. M., and Whisnant, J. P.:  Cerebellar Ataxia and Neuronitis After Exposure to DDT and Lindane , Proc. Staff Meet. Mayo Clin. 32:67, 1957;.

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