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Clinical Enzymology.

AMA Am J Dis Child. 1958;96(3):416. doi:10.1001/archpedi.1958.02060060418024.
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For many of us practicing physicians the term "enzymes" refers to vague chemical substances found in the laboratories of the biochemists. Many use the term as an even more vague explanation for certain phenomena. How often does one hear the following: "No one knows what the explanation is. It must be an enzyme"!

It is an arresting experience, therefore, to come across a book with the title "Clinical Enzymology," and it is impressive to read how much of clinical science from both the diagnostic and therapeutic aspects is directly involved with enzymology today. Consider, for example, the parenteral use of trypsin in occlusive peripheral vascular disease. The book presents impressive "before and after" pictures illustrating its use parenterally in cases of decubitus ulcers, thrombophlebitis, and varicose ulcers. However, as in many other fields, the interpretation of the results of studies in which this agent was used are not always clear


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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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