August 1958, Vol 96, No. 2 >

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Article | August 1958

Salt-Losing Nephritis

IRWIN GRIBETZ, M.D.; SEYMOUR RITTER, M.D.; MILTON J. H. GRAND, M.D.

AMA Am J Dis Child. 1958;96(2):191-196. doi:10.1001/archpedi.1958.02060060193010.

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Salt-losing nephritis is one of many clinical situations involving electrolyte disturbance in renal disease. This type of nephropathy is characterized by hyponatremia and hypochloremia, lassitude, thirst, polyuria, azotemia, and circulatory collapse. The syndrome was first described by Thorn, Koepf, and Clinton¹ in 1944. Since then, 15 additional cases have been reported^2-11 which satisfy the criteria of Levere and Wesson⁹ for salt-losing nephropathies.

The purpose of this report is to present the first case of salt-losing nephritis in the pediatric age group and to outline the therapeutic regimen based on the pathophysiology of the syndrome.

Report of Case A 12-year-old white boy was admitted to Montefiore Hospital on Aug. 10, 1956, for the third time because of expectoration of bloody material. The first two admissions were on the private service on April 7, 1956, and July 11, 1956, for anemia.He was transfused on each admission but received

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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GRIBETZ I, RITTER S, GRAND MH. Salt-Losing Nephritis. AMA Am J Dis Child. 1958;96(2):191-196. doi:10.1001/archpedi.1958.02060060193010.

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