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June 1958, Vol 95, No. 6 >
Article | June 1958

The Effect of a Corn Oil-Evaporated Milk Mixture on Serum Cholesterol Levels in Infancy FREE

JULIUS POMERANZE, M.D.; ALTA GOALWIN, M.D.; LAWRENCE B. SLOBODY, M.D.
[+] Author Affiliations

Received for publication Dec. 28, 1957.

Supported by a grant from the Lipotropic Research Foundation.


AMA Am J Dis Child. 1958;95(6):622-625. doi:10.1001/archpedi.1958.02060050626006.
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References
Comments

The group of substances known as the essential fatty acids (EFA) have recently become a central focus of research and interest in human nutrition. Of these linoleic, linolenic, and arachidonic are most commonly available in food and therefore of most practical importance. The original work with these acids, in dermatology, resulted in conflicting findings.1-3 At the present, attention is concentrated on their role in relation to fat metabolism and consequently is directed toward their possible impact on atherosclerosis.

Sinclair4 proposed that a disproportionate intake of saturated and unsaturated fats produces lipidemia through excessive esterification of cholesterol with saturated fatty acids, the products of which are not easily metabolized. It has been demonstrated in humans that high-vegetable-fat diets5 and artificial diets containing corn oil6 significantly lower serum cholesterol levels. The clinical importance of these findings resides in the at present enigmatic interrelationship between diet, cholesteremia, and atherosclerosis.

REFERENCES

1 +
Hansen, A. E.:  Serum Lipids in Eczema and in Other Pathologic Conditions , Am. J. Dis. Child. 53:933-946, 1937;.
2 +
Ginsberg, J. E.; Bernstein, C., Jr., and Iob, L. V.:  Effect of Oils Containing Unsaturated Fatty Acids on Patients with Dermatitis: with a Brief Report of an Experimental Study in Guinea-Pigs , Arch. Dermat.& Syph. 36:1033-1038, 1937;.
3 +
Taub, S. J., and Zakon, S. J.:  The Use of Unsaturated Fatty Acids in the Treatment of Eczema (Atopic Dermatitis, Neurodermatitis) , J. A. M. A. 105:1675, 1935;.
4 +
Sinclair, H. M.:  Deficiency of Essential Fatty Acids and Atherosclerosis, Etcetera , Letters to the Editor, Lancet 1:381-383, 1956;.
5 +
Groen, J.; Tjiong, B. K.; Kamminga, C. E., and Willebrands, A. F.:  The Influence of Nutrition, Individuality, and Some Other Factors, Including Various Forms of Stress, on the Serum Cholesterol: An Experiment of 9 Months' Duration in 60 Normal Volunteers , Voeding 13:556-587, 1952;.
6 +
Ahrens, E. H., Jr.; Blankenhorn, D. H., and Tsaltas, T. T.:  Effect on Human Serum Lipids of Substituting Plant for Animal Fat in Diet , Proc. Soc. Exper. Biol. & Med. 86:872-878, 1954;.
7 +
Pomeranze, J.; Goalwin, A., and Slobody, L. B.: To be published.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Hansen, A. E.:  Serum Lipids in Eczema and in Other Pathologic Conditions , Am. J. Dis. Child. 53:933-946, 1937;.
2 +
Ginsberg, J. E.; Bernstein, C., Jr., and Iob, L. V.:  Effect of Oils Containing Unsaturated Fatty Acids on Patients with Dermatitis: with a Brief Report of an Experimental Study in Guinea-Pigs , Arch. Dermat.& Syph. 36:1033-1038, 1937;.
3 +
Taub, S. J., and Zakon, S. J.:  The Use of Unsaturated Fatty Acids in the Treatment of Eczema (Atopic Dermatitis, Neurodermatitis) , J. A. M. A. 105:1675, 1935;.
4 +
Sinclair, H. M.:  Deficiency of Essential Fatty Acids and Atherosclerosis, Etcetera , Letters to the Editor, Lancet 1:381-383, 1956;.
5 +
Groen, J.; Tjiong, B. K.; Kamminga, C. E., and Willebrands, A. F.:  The Influence of Nutrition, Individuality, and Some Other Factors, Including Various Forms of Stress, on the Serum Cholesterol: An Experiment of 9 Months' Duration in 60 Normal Volunteers , Voeding 13:556-587, 1952;.
6 +
Ahrens, E. H., Jr.; Blankenhorn, D. H., and Tsaltas, T. T.:  Effect on Human Serum Lipids of Substituting Plant for Animal Fat in Diet , Proc. Soc. Exper. Biol. & Med. 86:872-878, 1954;.
7 +
Pomeranze, J.; Goalwin, A., and Slobody, L. B.: To be published.

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