0
April 1958, Vol 95, No. 4 >
Article | April 1958

Addison's Disease in Three Six-Year-Old Boys FREE

BERNARD MATHIS MALLOY, M.D.; CALVIN W. WOODRUFF, M.D.
[+] Author Affiliations

Received for publication Oct. 2, 1957; accepted Nov. 4.

This patient was referred by Dr. James C. Overall.


AMA Am J Dis Child. 1958;95(4):364-369. doi:10.1001/archpedi.1958.02060050366004.
Text Size: A A A
Published online
Article
References
Comments

Addison's disease is rare in childhood. In reviewing the literature prior to June, 1945, Jaudon1 found 12 cases in children aged 10 years or less. Since that time only 12 cases have been reported in the available literature.2-11 Cases of adrenal failure associated with the adrenogenital syndrome were excluded, as were cases occurring before the age of 2 years, because these appear to be a separate group of patients.12 Among these 12 cases reported, 5 were associated with hypoparathyroidism or moniliasis or had a sibling with this combination of diseases.8-11 Four of these five occurred in two families in which other cases of "the syndrome of familial juvenile hypoadrenocorticism and superficial moniliasis"13 occurred. In none of these cases associated with hypoparathyroidism and/or moniliasis was tuberculous involvement of the adrenal found. Tuberculosis is becoming an unusual cause of Addison's disease in childhood, as it has become in

REFERENCES

1 +
Jaudon, J. C.:  Addison's Disease in Children , J. Pediat. 28:737-755, 1946;.
2 +
Burdick, W. F.; Warthen, R. O.; Cassidy, J. E., and Welsh, W. W.:  Addison's Disease in a 5½-Year-Old Boy , Am. J. Dis. Child. 80:975-981, 1950;.
3 +
White, F. P., and Sutton, L. E.:  Addison's Disease in a Negro Child , J. Pediat. 37:778-782, 1950;.
4 +
Russell, A., and Potter, C. T.:  Addison's Disease in Childhood , Proc. Roy. Soc. Med. 44:957-960, 1951;.
5 +
Mautner, H.:  Addisonian Crisis in a Boy of 4 Years of Age , Bibl. paediat. Basel. , No. (58) , pp. 354-360, 1954;.
6 +
Bickel, H., and Stamm, O.:  Über einem Fall von Morbus Addison im Kindesalter infolge Nebennierencirrhose , Helvet. pædiat. acta 3:53-63, 1948;.
7 +
Bie, J.:  Morbus Addisonii hos børn: Forekomst hos 2 søskende , Nord. med. 55:193-198, 1956;.
8 +
Talbot, N. B.; Butler, A. M., and MacLachlan, E. A.:  The Effect of Testosterone and Allied Compounds on the Mineral, Nitrogen, and Carbohydrate Metabolism of a Girl with Addison's Disease , J. Clin. Invest. 22:583-593, 1943;.
9 +
Craig, J. M.; Schiff, L. H., and Boone, J. E.:  Chronic Moniliasis Associated with Addison's Disease , A. M. A. Am. J. Dis. Child. 89:669-684, 1955;.
10 +
 Cabot Case 40361 , New England J. Med. 251:442-448, 1954;.
11 +
DiGeorge, A. M., and Paschkis, K.:  The Syndrome of Addison's Disease, Hypoparathyroidism, and Superficial Moniliasis , A. M. A. Am. J. Dis. Child. 94:476-478, 1957;.
12 +
Williams, A., and Robinson, M. J.:  Addison's Disease in Infancy , Arch. Dis. Childhood 31:265-269, 1956;.
13 +
Whitaker, J.; Landing, B. H.; Esselborn, V. M., and Williams, R. R.:  The Syndrome of Familial Juvenile Hypoadrenolcorticism, Hypoparathyroidism and Superficial Moniliasis , J. Clin. Endocrinol. 16:1374-1387, 1956;.
14 +
Harrison, H. E., and Darrow, D. C.:  The Distribution of Body Water and Electrolytes in Adrenal Insufficiency , J. Clin. Invest. 17:77-86, 1938;.
15 +
Darrow, D. C.; Harrison, H. E., and Taffel, M.:  Tissue Electrolytes in Adrenal Insufficiency , J. Biol. Chem. 130:487-502, 1939;.
16 +
Muntwyler, E.; Mellors, R. C.; Mautz, F. R., and Mangun, G. H.:  Electrolyte and Water Equilibria in the Dog: II. Electrolyte and Water Exchange Between Skeletal Muscle and Blood in Adrenal Insufficiency , J. Biol. Chem. 134:367-387, 1940;.
17 +
Buell, M. V., and Turner, E.:  Cation Distribution in the Muscles of Adrenalectomized Rats , Am. J. Physiol. 134:225-239, 1941;.
18 +
Swingle, W. W.; Parkins, W. M.; Taylor, A. R., and Hays, H. W.:  A Study of Water Intoxication in the Intact and Adrenalectomized Dog and the Influence of Adrenal Cortical Hormone upon Fluid and Electrolyte Distribution , Am. J. Physiol. 119:557-566, 1937;.
19 +
Hills, A. G.; Chalmers, T. M.; Webster, G. D., Jr., and Rosenthal, O. H.:  Adrenal Cortical Regulation of the Distribution of Water and Electrolytes in the Human Body , J. Clin. Invest. 32:1236-1247, 1953;.
20 +
Wilson, G. M., and Miller, H. E.:  Exchangeable Sodium in Addison's Disease in Relation to the Electrocardiogram and the Action of Cortisone , Clin. Sc. 12:113-129, 1953;.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

1 +
Jaudon, J. C.:  Addison's Disease in Children , J. Pediat. 28:737-755, 1946;.
2 +
Burdick, W. F.; Warthen, R. O.; Cassidy, J. E., and Welsh, W. W.:  Addison's Disease in a 5½-Year-Old Boy , Am. J. Dis. Child. 80:975-981, 1950;.
3 +
White, F. P., and Sutton, L. E.:  Addison's Disease in a Negro Child , J. Pediat. 37:778-782, 1950;.
4 +
Russell, A., and Potter, C. T.:  Addison's Disease in Childhood , Proc. Roy. Soc. Med. 44:957-960, 1951;.
5 +
Mautner, H.:  Addisonian Crisis in a Boy of 4 Years of Age , Bibl. paediat. Basel. , No. (58) , pp. 354-360, 1954;.
6 +
Bickel, H., and Stamm, O.:  Über einem Fall von Morbus Addison im Kindesalter infolge Nebennierencirrhose , Helvet. pædiat. acta 3:53-63, 1948;.
7 +
Bie, J.:  Morbus Addisonii hos børn: Forekomst hos 2 søskende , Nord. med. 55:193-198, 1956;.
8 +
Talbot, N. B.; Butler, A. M., and MacLachlan, E. A.:  The Effect of Testosterone and Allied Compounds on the Mineral, Nitrogen, and Carbohydrate Metabolism of a Girl with Addison's Disease , J. Clin. Invest. 22:583-593, 1943;.
9 +
Craig, J. M.; Schiff, L. H., and Boone, J. E.:  Chronic Moniliasis Associated with Addison's Disease , A. M. A. Am. J. Dis. Child. 89:669-684, 1955;.
10 +
 Cabot Case 40361 , New England J. Med. 251:442-448, 1954;.
11 +
DiGeorge, A. M., and Paschkis, K.:  The Syndrome of Addison's Disease, Hypoparathyroidism, and Superficial Moniliasis , A. M. A. Am. J. Dis. Child. 94:476-478, 1957;.
12 +
Williams, A., and Robinson, M. J.:  Addison's Disease in Infancy , Arch. Dis. Childhood 31:265-269, 1956;.
13 +
Whitaker, J.; Landing, B. H.; Esselborn, V. M., and Williams, R. R.:  The Syndrome of Familial Juvenile Hypoadrenolcorticism, Hypoparathyroidism and Superficial Moniliasis , J. Clin. Endocrinol. 16:1374-1387, 1956;.
14 +
Harrison, H. E., and Darrow, D. C.:  The Distribution of Body Water and Electrolytes in Adrenal Insufficiency , J. Clin. Invest. 17:77-86, 1938;.
15 +
Darrow, D. C.; Harrison, H. E., and Taffel, M.:  Tissue Electrolytes in Adrenal Insufficiency , J. Biol. Chem. 130:487-502, 1939;.
16 +
Muntwyler, E.; Mellors, R. C.; Mautz, F. R., and Mangun, G. H.:  Electrolyte and Water Equilibria in the Dog: II. Electrolyte and Water Exchange Between Skeletal Muscle and Blood in Adrenal Insufficiency , J. Biol. Chem. 134:367-387, 1940;.
17 +
Buell, M. V., and Turner, E.:  Cation Distribution in the Muscles of Adrenalectomized Rats , Am. J. Physiol. 134:225-239, 1941;.
18 +
Swingle, W. W.; Parkins, W. M.; Taylor, A. R., and Hays, H. W.:  A Study of Water Intoxication in the Intact and Adrenalectomized Dog and the Influence of Adrenal Cortical Hormone upon Fluid and Electrolyte Distribution , Am. J. Physiol. 119:557-566, 1937;.
19 +
Hills, A. G.; Chalmers, T. M.; Webster, G. D., Jr., and Rosenthal, O. H.:  Adrenal Cortical Regulation of the Distribution of Water and Electrolytes in the Human Body , J. Clin. Invest. 32:1236-1247, 1953;.
20 +
Wilson, G. M., and Miller, H. E.:  Exchangeable Sodium in Addison's Disease in Relation to the Electrocardiogram and the Action of Cortisone , Clin. Sc. 12:113-129, 1953;.

Correspondence

Submit a Letter
CME
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Clear Answers | Save For Later
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Compression-Only CPR: Pushing the Science Forward
Cone
AAM 2010;304:1493-1495.
All you need to read in the other general journals
BMJ 2010;341:c5893-c1494.
Submit a Comment

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

© 2013 American Medical Association. All Rights Reserved.
Powered bySilverchair Information Systems