0
Article |

Acute Adrenal Insufficiency Due to Congenital Defect FREE

H. E. MacMAHON, M.D.; RICHARD WAGNER, M.D.; DAVID B. WEINER, M.D.
[+] Author Affiliations

Received for publication Nov. 16, 1956; revised March 26, 1957; accepted May 5.

Read by title before the Sixty-Sixth Annual Meeting of the American Pediatric Society, Buck Hill Falls, Pa., May 9-11, 1956.

The autopsy was performed by Drs. J. McGovern and H. E. MacMahon.


AMA Am J Dis Child. 1957;94(3):282-285. doi:10.1001/archpedi.1957.04030040068010.
Text Size: A A A
Published online

Transient adrenal insufficiency in early infancy has been described by Jaudon.1 Congenital hypoplasia as the cause of fatal adrenal failure is the least understood condition among the various etiological possibilities. The following study may be contributory to the understanding of the pathology of this rare condition and of the interrelation between the electrolyte-controlling mechanism and the histopathological changes of the adrenal cortex.

Report of Case  A white boy weighing 8 lb. 12 oz. at birth began vomiting, having diarrhea, and losing weight at the age of 2 weeks and was admitted to the hospital a week later in severe shock with diarrhea and dehydration. The skin was grayish, and the child appeared lethargic. The weight was 13 oz. below the birth weight. The genitalia were normal. A slight trace of albumin was found in the urine; tests for sugar and sediment were negative. Blood chemistry studies showed sodium, 120

REFERENCES

Jaudon, J. C.:  Hypofunction of Adrenals in Early Life , J. Pediat. 29:696, 1946;.
Kampmeier, O. F.:  Giant Epithelial Cells of the Human Fetal Adrenal , Anat. Rec. 37:95, 1927;.
Craig, J. M., and Landing, B. H.:  Anaplastic Cells of Fetal Adrenal Cortex , Am. J. Clin. Path. 21:940, 1951;.
Beatty, E. C., Jr., and Hawes, C. R.:  Cytomegaly of the Adrenal Gland , A. M. A. Am. J. Dis. Child. 89:463, 1955;.
Reddy, W. J.:  Modification of the Reddy-Jenkins-Thorn Method for the Estimation of 17-Hydroxycorticoids in Urine , Metabolism 3:489, 1954;.

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

Jaudon, J. C.:  Hypofunction of Adrenals in Early Life , J. Pediat. 29:696, 1946;.
Kampmeier, O. F.:  Giant Epithelial Cells of the Human Fetal Adrenal , Anat. Rec. 37:95, 1927;.
Craig, J. M., and Landing, B. H.:  Anaplastic Cells of Fetal Adrenal Cortex , Am. J. Clin. Path. 21:940, 1951;.
Beatty, E. C., Jr., and Hawes, C. R.:  Cytomegaly of the Adrenal Gland , A. M. A. Am. J. Dis. Child. 89:463, 1955;.
Reddy, W. J.:  Modification of the Reddy-Jenkins-Thorn Method for the Estimation of 17-Hydroxycorticoids in Urine , Metabolism 3:489, 1954;.

Correspondence

CME
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.