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Relationships of Cerebral Disorder to Faults in Dental Enamel FREE

W. F. VIA, D.D.S.; J. A. CHURCHILL, M.D.
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Received for publication April 9, 1957; accepted May 5.


AMA Am J Dis Child. 1957;94(2):137-142. doi:10.1001/archpedi.1957.04030030031006.
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The origins of cerebral disorders in children are often difficult to discover. Causes of brain damage may be suspected, but the lack of confirmatory evidence leaves doubt that a suspected cause was, in fact, responsible for the abnormalities observed. To have a way of confirming suspected causes of early brain damage would be a great advantage. The thought occurred to us that some of the abnormal processes causing damage to the brain might also produce defects in the enamel forming on the teeth at the time. Since the chronological pattern of enamel growth has been established,1 the amount of enamel formed at a given age being known, it should be possible to tell when a disturbance had occurred which caused the enamel fault. Hence, a study was begun to determine the correlation of cerebral disorders and enamel faults. If a correlation exists, the observed enamel faults in combination with

REFERENCES

Schour, I., and Massler, M.:  The Growth Pattern of Human Teeth , Am. Dent. A. J. 27:1778 ( (Nov.) ) 1940;.
Magitat, M.:  Honey-Combed Teeth Regarded as Evidence of Infantile Convulsions , Brit. J. Dent. Sc. 24:939 ( (March) ) 1881;.
Kronfeld, R., and Schour, I.:  Neonatal Dental Hypoplasia , Am. Dent. A. J. 26:18 ( (Jan.) ) 1939;.
Sheldon, M.; Bibby, B., and Bales, M.:  The Relationship Between Microscopic Enamel Defects and Infantile Disabilities , J. Dent. Res. 24:109 ( (Feb.) ) 1945;.
Bevelander, G., and Bernstein, J.:  The Effect of Artificially Induced Fever on the Structure of the Developing Tooth of the Rat , J. Dent. Res. 19:155 ( (Feb.) ) 1940;.
Sarnat, B., and Schour, I.:  Enamel Hypoplasia (Chronologic Enamel Aplasia in Relation to Systemic Disease) , Am. Dent. A. J. 28:1989 ( (Dec.) ) 1941;
29:147 (Jan.) 1942.
Kreshover, S.:  The Pathogenesis of Enamel Hypoplasia: An Experimental Study , J. Dent. Res. 23:231 ( (March) ) 1944;.
Kreshover, S.; Clough, W., and Bear, D.:  Prenatal Influences on Tooth Development: I. Alloxan Diabetes in Rats , J. Dent. Res. 32:246 ( (June) ) 1953;.
Kreshover, S., and Clough, W.:  Prenatal Influences on Tooth Development: II. Artificially Induced Fevers , J. Dent. Res. 32:505 ( (Sept.) ) 1953;.
Kreshover, S., and Clough, W.:  Vaccinia Infection in Pregnant Rabbits and Its Effect on Natural and Fetal Dental Tissues , Am. Dent. A. J. 49:549 ( (April) ) 1954;.
Kreshover, S., and Hancock, J.:  The Effect of Lymphocytic Choriomeningitis on Pregnancy and Dental Tissues in Mice , J. Dent. Res. 35:467 ( (June) ) 1956;.
Marshall-Day, C. D.:  Nutritional Deficiencies and Dental Caries in Northern India , Brit. Dent. J. 76:115 ( (Jan.) ) 1944;.
Forrester, R., and Miller, J.:  Dental Changes Associated with Kernicterus , Arch. Dis. Childhood 30:224 ( (Feb.) ) 1955;.
Miller, J.:  Pigmentation of Teeth Due to Rhesus Factor , Brit. Dent. J. 91:121 ( (Jan.) ) 1951;.
Logan, W., and Kronfeld, R.: Oral Histology and Embryology , Ed. 2, St. Louis, The C. V. Mosby Company, 1949;, p. 305, Table VIII.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

Schour, I., and Massler, M.:  The Growth Pattern of Human Teeth , Am. Dent. A. J. 27:1778 ( (Nov.) ) 1940;.
Magitat, M.:  Honey-Combed Teeth Regarded as Evidence of Infantile Convulsions , Brit. J. Dent. Sc. 24:939 ( (March) ) 1881;.
Kronfeld, R., and Schour, I.:  Neonatal Dental Hypoplasia , Am. Dent. A. J. 26:18 ( (Jan.) ) 1939;.
Sheldon, M.; Bibby, B., and Bales, M.:  The Relationship Between Microscopic Enamel Defects and Infantile Disabilities , J. Dent. Res. 24:109 ( (Feb.) ) 1945;.
Bevelander, G., and Bernstein, J.:  The Effect of Artificially Induced Fever on the Structure of the Developing Tooth of the Rat , J. Dent. Res. 19:155 ( (Feb.) ) 1940;.
Sarnat, B., and Schour, I.:  Enamel Hypoplasia (Chronologic Enamel Aplasia in Relation to Systemic Disease) , Am. Dent. A. J. 28:1989 ( (Dec.) ) 1941;
29:147 (Jan.) 1942.
Kreshover, S.:  The Pathogenesis of Enamel Hypoplasia: An Experimental Study , J. Dent. Res. 23:231 ( (March) ) 1944;.
Kreshover, S.; Clough, W., and Bear, D.:  Prenatal Influences on Tooth Development: I. Alloxan Diabetes in Rats , J. Dent. Res. 32:246 ( (June) ) 1953;.
Kreshover, S., and Clough, W.:  Prenatal Influences on Tooth Development: II. Artificially Induced Fevers , J. Dent. Res. 32:505 ( (Sept.) ) 1953;.
Kreshover, S., and Clough, W.:  Vaccinia Infection in Pregnant Rabbits and Its Effect on Natural and Fetal Dental Tissues , Am. Dent. A. J. 49:549 ( (April) ) 1954;.
Kreshover, S., and Hancock, J.:  The Effect of Lymphocytic Choriomeningitis on Pregnancy and Dental Tissues in Mice , J. Dent. Res. 35:467 ( (June) ) 1956;.
Marshall-Day, C. D.:  Nutritional Deficiencies and Dental Caries in Northern India , Brit. Dent. J. 76:115 ( (Jan.) ) 1944;.
Forrester, R., and Miller, J.:  Dental Changes Associated with Kernicterus , Arch. Dis. Childhood 30:224 ( (Feb.) ) 1955;.
Miller, J.:  Pigmentation of Teeth Due to Rhesus Factor , Brit. Dent. J. 91:121 ( (Jan.) ) 1951;.
Logan, W., and Kronfeld, R.: Oral Histology and Embryology , Ed. 2, St. Louis, The C. V. Mosby Company, 1949;, p. 305, Table VIII.

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