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Primary Staphylococcal Enterocolitis

AMA Am J Dis Child. 1957;93(5):526-529. doi:10.1001/archpedi.1957.02060040528005.
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An increasing number of cases of staphylococcal enterocolitis, often fatal, have been reported in the past few years following major abdominal surgery and/or after the administration of antibiotics.1 Earlier, before the introduction of antibiotics, cases of a similar nature occurring with or without surgery were reported, but no evidence was presented to indicate that they were caused by Staphylococcus aureus.2,3 This may be due to the fact that most stool cultures in the past were performed using special bacteriological media designed to inhibit the growth of the Gram-positive organisms in the feces and thus failed to permit growth of Staph. aureus. In 1947 Selberg4 reported a case of fatal staphylococcal enteritis in an infant receiving no antibiotics who was breast fed from a mother who had a staphylococcal mastitis. Cultures of the infant's stool yielded mainly Staph. aureus.

The clinical course and laboratory and pathologic findings in


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