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Epiphysiolysis

JOSEPH A. JOHNSTON, M.D.; GORDON MANSON, M.D.; C. LESLIE MITCHELL, M.D.
AMA Am J Dis Child. 1956;92(4):337-346. doi:10.1001/archpedi.1956.02060030331003.
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The sharp limitation of the occurrence of slipping of the upper femoral epiphysis to the accelerative phase of the pubertal growth spurt, such variations as occur duplicating strikingly a frequency curve of the time of occurrence of the "year of maximum growth—the MG year"1 (Fig. 1), suggests conditioning of the episode by a metabolic abnormality peculiar to this period. The fact that it occurs most frequently in the overweight child recalls an old observation of a reciprocal relationship between gain in weight and calcium retention2; the more rapidly the growing animal was permitted to gain in weight, the more florid the rickets that resulted from the Steenbock diet. A similar phenomenon is observed when testosterone is administered to the normal boy; marked increase in the retention of nitrogen is accompanied by reciprocal fall in calcium storage.3 It is the thesis of this paper that suboptimal mineralization is

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