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July 1956, Vol 92, No. 1 >
Article | July 1956

The Iodized Oil (Lipiodol) Test for Fat Absorption FREE

G. E. DELORY, Ph.D.; S. ISRAELS, F.R.C.P.(C); H. JONASSON, B.Sc.
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Submitted for publication Feb. 9, 1956.


AMA Am J Dis Child. 1956;92(1):24-26. doi:10.1001/archpedi.1956.02060030026007.
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Introduction  Following the use of the administration of iodized oils as a test for fat absorption, Silverman and Shirkey1 introduced a simple modification in which a qualitative test for iodine was performed on varying dilutions of urine collected 12-18 hours following oral ingestion of iodized oil (Lipiodol). They claimed that a positive test for iodine after the ingestion of iodized oil in a dilution of 1 in 4 or greater probably excludes fibrocystic disease of the pancreas as a diagnosis. Our experience with this test was most disappointing, negative results on undiluted urine being often found even with urine of normal controls.We therefore tried the effect of determining the urine iodine quantitatively while preserving the simplicity of the Silverman-Shirkey technique.

Experimental Procedure  Iodized oil was administered to patients in the Children's Hospital, Winnipeg, in the manner described by Silverman and Shirkey. Samples of urine were collected before and

REFERENCES

1 +
Silverman, F. N., and Shirkey, H. C.:  A Fat Absorption Test Using Iodized Oil with Particular Application as a Screening Test in the Diagnosis of Fibrocystic Disease of the Pancreas , Pediatrics 15:143, 1955;.
2 +
Alpert, L. K.:  A Rapid Method for the Determination of Diodrast-Iodine in Blood and Urine , Bull. Johns Hopkins Hosp. 68:522, 1941;.

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References

1 +
Silverman, F. N., and Shirkey, H. C.:  A Fat Absorption Test Using Iodized Oil with Particular Application as a Screening Test in the Diagnosis of Fibrocystic Disease of the Pancreas , Pediatrics 15:143, 1955;.
2 +
Alpert, L. K.:  A Rapid Method for the Determination of Diodrast-Iodine in Blood and Urine , Bull. Johns Hopkins Hosp. 68:522, 1941;.

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