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NITROFURANTOIN THERAPY OF URINARY TRACT INFECTIONS IN CHILDREN

S. HARRIS JOHNSON III, M.D.; MATTHEW MARSHALL Jr., M.D.
AMA Am J Dis Child. 1955;89(2):199-201. doi:10.1001/archpedi.1955.02050110241010.
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FURADANTIN, a brand of nitrofurantoin N. N. R., has been demonstrated to be an effective urinary antibacterial agent in adults * and we have found it to be equally efficacious in children, as shown in the following study.

Thirty-eight children hospitalized at either Children's Hospital or Western Pennsylvania Hospital were given nitrofurantoin for urinary tract infections. Nine of these patients were not under observation sufficiently long to evaluate the results. Nitrofurantoin was administered during 33 episodes of urinary tract infections in 29 patients, and the results of this treatment are summarized in Tables 1 and 2. Nitrofurantoin in both the liquid (Furadantin Pediatric Suspension) and tablet forms was utilized. Children who could ingest them preferred the tablets. The liquid was thought unpalatable by some, but none were intolerant of it. The liquid caused a sensation of gastric irritation in two children, but this subsided when the dosage was reduced to 6

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