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December 1954, Vol 88, No. 6 >
Article | December 1954

CONGENITAL LEUKEMIA FREE

ROBERT E. O'CONNOR, M.D.; ROBERT W. McKEY, M.D.; JACK SMITH, M.D.
[+] Author Affiliations

References 1-8.


AMA Am J Dis Child. 1954;88(6):740-742. doi:10.1001/archpedi.1954.02050100742005.
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REFERENCES to congenital leukemia are few in number.* Bernhard, Gore, and Kilby,9 in reviewing the literature in 1951, found 14 acceptable cases and added 4 of their own. In 1952, Casilli, Rumsey, and Satulsky10 reported a case of myeloblastic leukemia in the neonatal period. The criteria for acceptance as a case of congenital leukemia are not too clearly defined, but the presence of leukemia cells in the peripheral blood, bone marrow, and visceral organs of an infant in the neonatal period is highly suggestive. It is the purpose of this paper to report a case of congenital leukemia in a 5-day-old boy, with septicemia as a terminal event.

REPORT OF CASE  The infant was born at this hospital after a labor of approximately four hours. The mother was an Rh-positive 19-year-old woman, unipara and secundagravida, whose Kline and Kahn reactions were negative. Total length of pregnancy was estimated

REFERENCES

1 +
Cross, F. S.:  Congenital Leucemia: A Report of 2 Cases , J. Pediat. 24:191-194, 1944;.
2 +
Giblin, J.:  A Case of Myelogenous Leukemia Occurring in an Infant 5 Weeks Old , Arch. Pediat. 50:662-665, 1933;.
3 +
Keith, H. M.:  Chronic Myelogenous Leukemia in Infancy , Am. J. Dis. Child. 69:366-368, 1945;.
4 +
Kelsey, W. M., Jr., and Anderson, D. H.:  Congenital Leukemia , Am. J. Dis. Child. 58: 1268-1277, 1939;.
5 +
Smith, L. W.:  Acute Leukemia in an Infant , Am. J. Dis. Child. 21:163-166, 1921;.
6 +
White, P. J., and Burn, E. L.:  Fatal Acute Lymphoblastic Leukemia with Great Enlargement of the Kidneys in an Infant 3 Weeks Old , Am. J. Dis. Child. 41:866-870, 1931;.
7 +
Baumann, T.:  Case of Congenital Leukemia , Schweiz. med. Wchnschr. 81:1121, 1950;.
8 +
Grislain, J. R., and Harrousseau, J.:  Acute Leukemia in the Newborn Infant , Nourrisson 38:270-286, 1950;.
9 +
Bernhard, W. G.; Gore, T., and Kilby, R. A.:  Congenital Leukemia , Blood 6:990-1001, 1951;.
10 +
Casilli, A. R.; Rumsey, W. L., and Satulsky, E. M.:  Acute Neonatal Myeloblastic Leukemia , A. M. A. Am. J. Dis. Child. 83:788-793, 1952;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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References

1 +
Cross, F. S.:  Congenital Leucemia: A Report of 2 Cases , J. Pediat. 24:191-194, 1944;.
2 +
Giblin, J.:  A Case of Myelogenous Leukemia Occurring in an Infant 5 Weeks Old , Arch. Pediat. 50:662-665, 1933;.
3 +
Keith, H. M.:  Chronic Myelogenous Leukemia in Infancy , Am. J. Dis. Child. 69:366-368, 1945;.
4 +
Kelsey, W. M., Jr., and Anderson, D. H.:  Congenital Leukemia , Am. J. Dis. Child. 58: 1268-1277, 1939;.
5 +
Smith, L. W.:  Acute Leukemia in an Infant , Am. J. Dis. Child. 21:163-166, 1921;.
6 +
White, P. J., and Burn, E. L.:  Fatal Acute Lymphoblastic Leukemia with Great Enlargement of the Kidneys in an Infant 3 Weeks Old , Am. J. Dis. Child. 41:866-870, 1931;.
7 +
Baumann, T.:  Case of Congenital Leukemia , Schweiz. med. Wchnschr. 81:1121, 1950;.
8 +
Grislain, J. R., and Harrousseau, J.:  Acute Leukemia in the Newborn Infant , Nourrisson 38:270-286, 1950;.
9 +
Bernhard, W. G.; Gore, T., and Kilby, R. A.:  Congenital Leukemia , Blood 6:990-1001, 1951;.
10 +
Casilli, A. R.; Rumsey, W. L., and Satulsky, E. M.:  Acute Neonatal Myeloblastic Leukemia , A. M. A. Am. J. Dis. Child. 83:788-793, 1952;.

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