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NEONATAL GLOMERULONEPHRITIS AND NEPHROTIC SYNDROME IN A 1,320-GM. PREMATURELY BORN INFANT

RALPH H. KUNSTADTER, M.D.; LOUIS ROSENBLUM, M.D.
AMA Am J Dis Child. 1954;88(5):611-617. doi:10.1001/archpedi.1954.02050100613008.
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ALTHOUGH the nephrotic syndrome in glomerulonephritis is common in early childhood, its occurrence in the neonatal period is extremely rare and, so far as we have been able to determine, has not been described in the literature in the newly born premature infant.

In 1930, Mitchell1 reviewed the literature on congenital nephritis and nephritis in the newborn infant and found a few cases in the foreign literature before or at the turn of the century.

Lapage,2 in 1932, reported a case of "hemorrhagic nephritis" in an 11-day-old full-term boy. The autopsy did not show glomerulonephritis. Conrad,3 in 1938, reported three cases of neonatal nephritis in full-term infants, with one death. No autopsy was obtained, and therefore the type of nephritis was not determined.

Montagna and Ausberg,4 in 1942, reported the case of a full-term boy dying on the 18th day with a clinical diagnosis of glomerulonephritis.

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