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EPENDYMOMA OF THE FOURTH VENTRICLE IN AN INFANT UNDER ONE YEAR OF AGE FREE

JEROME E. MAISEL, M.D.; STANLEY S. LAMM, M.D.
AMA Am J Dis Child. 1953;86(5):604-608. doi:10.1001/archpedi.1953.02050080617007.
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BRAIN tumors occur infrequently during the first years of life and usually are not recognized as such prior to surgical exploration or autopsy examination. In a recent hospital admission an infant was observed who presented signs and symptoms suggestive of a lesion in the cerebellopontine region. These findings, to be described more fully later, led to a presumptive diagnosis of a brain tumor which was later confirmed at autopsy.

REPORT OF CASE  G. W., an 11-month-old Negro girl, was admitted to Kings County Hospital (State University Division) on Oct. 27, 1951, because of a stiff neck of one day's duration.Approximately two weeks prior to admission the infant became anorectic, showed evidence of weight loss, and reacted with increased irritability on being handled. Three days prior to admission the mother observed that the infant had become less irritable, moderately lethargic, and unresponsive to environmental stimuli.No history of fever, cough,

REFERENCES

Bailey, P.; Buchanan, D. N., and Bucy, P. C.: Intracranial Tumors of Infancy and Childhood , Chicago, Univ. Chicago Press, 1939;.
Globus, J. H.; Zucker, J. M., and Rubinstein, J. M.:  Tumors of the Brain in Children and Adolescents: Clinical and Anatomic Survey of 92 Verified Cases , Am. J. Dis. Child. 65:604, 1943;.
French, L. A.:  Brain Tumors in Children , Minnesota Med. 31:867, 1948;.
Stern, R. O.:  Cerebral Tumours in Children , Arch. Dis. Childhood 12:291, 1937;.
Critchley, M.:  Brain Tumours in Children: Their General Symptomatology , Brit. J. Child. Dis. 22:251, 1925;.
Cushing, H.:  Intracranial Tumors of Preadolescence , Am. J. Dis. Child. 33:551, 1927;.
Smith, W. A., and Fincher, E. F.:  Intracranial Tumors in Children: Preliminary Study of 100 Cases , South. M. J. 35:547, 1942;.
Craig, W. M.; Keith, H. M., and Kernohan, J. W.:  Tumors of the Brain Occurring in Childhood , Acta psychiat. et neurol. scandinav. 24:375, 1949;.
Arnstein, L. H.: Boldrey, E., and Naffziger, H. C.:  Case Report and Survey of Brain Tumors During Neonatal Period , J. Neurosurg. 8:315, 1951;.
Leibner, I. W.:  Brain Tumors in Infancy , Pediatrics 1:346, 1948;.
Gross, S. W.:  Tumors of the Brain in Infancy: Clinical and Pathologic Study , Am. J. Dis. Child. 48:739, 1934;.
Footnotes 2, 3 and 4.
French.1c
Stern.1dd
Critchley.1ee
Cushing.1f
Smith and Fincher.1g
Craig, Keith, and Kernohan.1h
Arnstein, Boldrey, and Naffziger.2
Leibner.3
Gross.4
Scheinker, I. M.: Neurosurgical Pathology , Springfield, Charles C Thomas, 1948;.
Cleveland, D.: Brain Tumors in Children. Wisconsin M. J. 48:686, 1949;.
Canavan, M. M., and Hemsath, F. A.:  Glioma in the Fourth Ventricle of a Prematurely Born Infant , Arch. Neurol. & Psychiat. 26:1234, 1931;.
Fisher, E. R.; Hazard, J. B., and Gardner, W. J.:  Intracranial Ependymoma: Clinicopathologic Observations , Cleveland Clin. Quart. 18:260, 1951;.
Cooper, I. S.; Kernohan, J. W., and Craig, W. M.:  Tumors of the Medulla Oblongata , A. M. A. Arch. Neurol. & Psychiat. 67:269, 1952;.
Merritt, H. H.:  Cerebrospinal Fluid in Cases of Tumor of the Brain , Arch. Neurol. & Psychiat. 34:1175, 1935;.
Henderson, W. R., and de Gutiérrez-Mahoney, C. G.:  Cerebrospinal Fluid in 302 Cases of Intracranial Tumor, Abscess, and Subdural Haemotoma , Brit. M. J. 4668:1461, 1950;.
Footnotes la, b, d, and h and 6k and l.

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References

Bailey, P.; Buchanan, D. N., and Bucy, P. C.: Intracranial Tumors of Infancy and Childhood , Chicago, Univ. Chicago Press, 1939;.
Globus, J. H.; Zucker, J. M., and Rubinstein, J. M.:  Tumors of the Brain in Children and Adolescents: Clinical and Anatomic Survey of 92 Verified Cases , Am. J. Dis. Child. 65:604, 1943;.
French, L. A.:  Brain Tumors in Children , Minnesota Med. 31:867, 1948;.
Stern, R. O.:  Cerebral Tumours in Children , Arch. Dis. Childhood 12:291, 1937;.
Critchley, M.:  Brain Tumours in Children: Their General Symptomatology , Brit. J. Child. Dis. 22:251, 1925;.
Cushing, H.:  Intracranial Tumors of Preadolescence , Am. J. Dis. Child. 33:551, 1927;.
Smith, W. A., and Fincher, E. F.:  Intracranial Tumors in Children: Preliminary Study of 100 Cases , South. M. J. 35:547, 1942;.
Craig, W. M.; Keith, H. M., and Kernohan, J. W.:  Tumors of the Brain Occurring in Childhood , Acta psychiat. et neurol. scandinav. 24:375, 1949;.
Arnstein, L. H.: Boldrey, E., and Naffziger, H. C.:  Case Report and Survey of Brain Tumors During Neonatal Period , J. Neurosurg. 8:315, 1951;.
Leibner, I. W.:  Brain Tumors in Infancy , Pediatrics 1:346, 1948;.
Gross, S. W.:  Tumors of the Brain in Infancy: Clinical and Pathologic Study , Am. J. Dis. Child. 48:739, 1934;.
Footnotes 2, 3 and 4.
French.1c
Stern.1dd
Critchley.1ee
Cushing.1f
Smith and Fincher.1g
Craig, Keith, and Kernohan.1h
Arnstein, Boldrey, and Naffziger.2
Leibner.3
Gross.4
Scheinker, I. M.: Neurosurgical Pathology , Springfield, Charles C Thomas, 1948;.
Cleveland, D.: Brain Tumors in Children. Wisconsin M. J. 48:686, 1949;.
Canavan, M. M., and Hemsath, F. A.:  Glioma in the Fourth Ventricle of a Prematurely Born Infant , Arch. Neurol. & Psychiat. 26:1234, 1931;.
Fisher, E. R.; Hazard, J. B., and Gardner, W. J.:  Intracranial Ependymoma: Clinicopathologic Observations , Cleveland Clin. Quart. 18:260, 1951;.
Cooper, I. S.; Kernohan, J. W., and Craig, W. M.:  Tumors of the Medulla Oblongata , A. M. A. Arch. Neurol. & Psychiat. 67:269, 1952;.
Merritt, H. H.:  Cerebrospinal Fluid in Cases of Tumor of the Brain , Arch. Neurol. & Psychiat. 34:1175, 1935;.
Henderson, W. R., and de Gutiérrez-Mahoney, C. G.:  Cerebrospinal Fluid in 302 Cases of Intracranial Tumor, Abscess, and Subdural Haemotoma , Brit. M. J. 4668:1461, 1950;.
Footnotes la, b, d, and h and 6k and l.

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