0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Growth and Metabolism in Normal and Thyroid-Ablated Infant Rhesus Monkeys (Macaca Mulatta): VI. Iodine Metabolism in Normal and Thyroid-Ablated Infant Rhesus Monkeys (Macaca Mulatta)

DONALD E. PICKERING, M.D.; DELBERT A. FISHER, M.D.; KENNETH G. SCOTT, Ph.D.; GERTRUDE VAN WAGENEN, Ph.D.; FRANCIS SCOTT SMYTH, M.D.
AMA Am J Dis Child. 1953;86(5):574-586. doi:10.1001/archpedi.1953.02050080587003.
Text Size: A A A
Published online

As one of a series of integrated reports regarding the role of thyroid in growth and metabolism of normal and I131 thyroid-ablated infant rhesus monkeys,1 this communication presents quantitative aspects of iodine metabolism.

Earlier reports of thyroid function in rhesus monkeys are limited to observations on thyroidectomized mature animals,2 except in the study of Fleischmann and

(Footnotes continued on next page)

co-workers,2a where two 8-month-old animals were also observed. Of the reported studies,2 none have dealt with iodine metabolism per se, nor have they been concerned with the role of thyroid in growth and development. In all cases, thyroidectomy was achieved either by prolonged administration of thiouracil3 or by surgical means—the latter frequently being complicated by severe and often fatal hypoparathyroidism.4 When thiouracil was used, large doses (0.8 gm. per day) were found necessary to produce hypothyroidism and thyroid hyperplasia in adult animals,

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();