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FURTHER ELECTROENCEPHALOGRAPHIC STUDIES IN SICKLE CELL ANEMIA FREE

FONTAINE S. HILL, M.D.; BILLIE CAMP DAVIS, B.S.
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Supported by a grant from the United States Public Health Service.


AMA Am J Dis Child. 1952;84(2):214-217. doi:10.1001/archpedi.1952.02050020078008.
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IN A PREVIOUS communication,1 the electroencephalographic findings in sickle cell anemia were reported. Included in this study were eight patients who presented an exacerbation of the symptomatology of sickle cell disease and who, therefore, were considered to be in a state of sickle cell crisis. Since the electroencephalograms were abnormal for all eight of these patients, we felt that further evaluation of electroencephalographic patterns of patients with sickle cell crisis was indicated.

It is the purpose of this paper to present a heretofore unreported electroencephalographic finding and to analyze the electroencephalograms of 12 additional patients who had been hospitalized with signs and symptoms of sickle cell crisis. Evidence has been presented previously to correlate the nature of brain potentials with clinical manifestations in those patients with central nervous system symptoms of sickle cell anemia.

METHODS  The diagnosis of sickle cell anemia was established definitely in each case before it

REFERENCES

Hill, F. S.; Hughes, J. G., and Davis, B. C.:  Electroencephalographic Findings in Sickle Cell Anemia , Pediatrics 6:277, 1950;.
Davis, P. A.:  Technique and Evaluation of the Electroencephalogram , J. Neurophysiol. 4:92, 1941;.
Lindsley, D. B.:  Electrical Potentials in Brain of Children and Adults , J. Gen. Psychol. 19:285, 1938;
 Longitudinal Study of Occipital Alpha Rhythm in Normal Children: Frequency and Amplitude Standards , J. Genet. Psychol. 55:197, 1939;.
Bernhard, C. G., and Skoglund, C. R.:  On Alpha Frequency of Human Brain Potentials as Function of Age , Skandinav. Arch. Physiol. 82:178, 1939;.
Gibbs, E. L., and Gibbs, F. A.:  Electroencephalographic Changes with Age During Sleep ; abstracted in Electroencephalog. & Clin. Neurophysiol. 2:355, 1950;.
Kimmelstiel, P.:  Vascular Occlusion and Ischemic Infarction in Sickle Cell Disease , Am. J. M. Sc. 216:11, 1948;.
Hughes, J. G.; Diggs, L. W., and Gillespie, C. E.:  Involvement of the Nervous System in Sickle Cell Anemia , J. Pediat. 17:166, 1940;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

Hill, F. S.; Hughes, J. G., and Davis, B. C.:  Electroencephalographic Findings in Sickle Cell Anemia , Pediatrics 6:277, 1950;.
Davis, P. A.:  Technique and Evaluation of the Electroencephalogram , J. Neurophysiol. 4:92, 1941;.
Lindsley, D. B.:  Electrical Potentials in Brain of Children and Adults , J. Gen. Psychol. 19:285, 1938;
 Longitudinal Study of Occipital Alpha Rhythm in Normal Children: Frequency and Amplitude Standards , J. Genet. Psychol. 55:197, 1939;.
Bernhard, C. G., and Skoglund, C. R.:  On Alpha Frequency of Human Brain Potentials as Function of Age , Skandinav. Arch. Physiol. 82:178, 1939;.
Gibbs, E. L., and Gibbs, F. A.:  Electroencephalographic Changes with Age During Sleep ; abstracted in Electroencephalog. & Clin. Neurophysiol. 2:355, 1950;.
Kimmelstiel, P.:  Vascular Occlusion and Ischemic Infarction in Sickle Cell Disease , Am. J. M. Sc. 216:11, 1948;.
Hughes, J. G.; Diggs, L. W., and Gillespie, C. E.:  Involvement of the Nervous System in Sickle Cell Anemia , J. Pediat. 17:166, 1940;.

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