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May 1952, Vol 83, No. 5 >
Article | May 1952

ACETIC ACID AEROSOL IN TREATMENT OF PURULENT BRONCHIECTASIS DUE TO PSEUDOMONAS AERUGINOSA FREE

WILLIAM W. CURRENCE
[+] Author Affiliations

The interest of Mr. O. L. Weiser, Bacteriologist, Fitzsimons Army Hospital, and Mr. F. W. Church, Director of the Division of Industrial Medicine, University of Colorado School of Medicine, is acknowledged.


AMA Am J Dis Child. 1952;83(5):637-641. doi:10.1001/archpedi.1952.02040090083008.
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THE PURPOSE of this paper is to report the case of a patient with chronic bronchiectasis in which Pseudomonas aeruginosa was cultured repeatedly from the respiratory tract and in whom the use of an acetic acid aerosol produced marked clinical improvement after antibiotic therapy had failed.

Olsen1 describes aerosols as mists of medicated solutions, and when such mists are inhaled by a patient the therapy is called aerosol therapy. He also states that if aerosol therapy has merit it is because of the topical effect exerted by the inhaled preparations on the bronchial mucosa and the mixing of the preparation with purulent bronchopulmonary secretions. The commonly encountered Gram-positive organisms to be found in bronchiectatic secretions are pneumococci, hemolytic and nonhemolytic streptococci and staphylococci. The common Gram-negative bacteria include Escherichia coli, Hemophilus influenzae, Aerobacter aerogenes, and Klebsiella pneumoniae. On many occasions Gram-negative bacteria are not isolated from sputum cultures until

REFERENCES

1 +
Olsen, A. M.:  Administration of Antibiotic Preparations by the Aerosol Method: A Critical Evaluation , M. Clin. North America 32:1077 ( (July) ) 1948;.
2 +
Smith, D. T.:  Causes and Treatment of Otitis Media: I. Observations on 205 Cases Occurring in 613 Consecutive Hospital Admissions , Am. J. Dis. Child. 28:1 ( (July) ) 1924;.
3 +
Ochs, I. L.:  Treatment of External Otitis: A Simple and Effective Technic , J. A. M. A. 142:1361 ( (April 29) ) 1950;.
4 +
Owen, C. R.:  Acetic Acid Inhibition of Gram Negative Bacilli in Culture Media , J. Bact. 52:353 ( (Sept.) ) 1946;.
5 +
Gill, W. D.:  Otomycosis: Some Remarks Concerning its Prevelance, Symptomatology and Treatment , Ann. Otol. Rhin. & Laryng. 47:189 ( (March) ) 1938;.
6 +
Gill, W. D.:  Otomycosis , in Jackson, C., and Jackson, C. L.: Diseases of the Nose, Throat and Ear , Philadelphia, W. B. Saunders Company, 1945;, p. 243.
7 +
Bifulco, E.:  Pulmonary Bacillus Pyocyaneus (Pseudomonas Aeruginosa) Infection in and Adult with Recovery , New York J. Med. 49:1195 ( (May 15) ) 1949;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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References

1 +
Olsen, A. M.:  Administration of Antibiotic Preparations by the Aerosol Method: A Critical Evaluation , M. Clin. North America 32:1077 ( (July) ) 1948;.
2 +
Smith, D. T.:  Causes and Treatment of Otitis Media: I. Observations on 205 Cases Occurring in 613 Consecutive Hospital Admissions , Am. J. Dis. Child. 28:1 ( (July) ) 1924;.
3 +
Ochs, I. L.:  Treatment of External Otitis: A Simple and Effective Technic , J. A. M. A. 142:1361 ( (April 29) ) 1950;.
4 +
Owen, C. R.:  Acetic Acid Inhibition of Gram Negative Bacilli in Culture Media , J. Bact. 52:353 ( (Sept.) ) 1946;.
5 +
Gill, W. D.:  Otomycosis: Some Remarks Concerning its Prevelance, Symptomatology and Treatment , Ann. Otol. Rhin. & Laryng. 47:189 ( (March) ) 1938;.
6 +
Gill, W. D.:  Otomycosis , in Jackson, C., and Jackson, C. L.: Diseases of the Nose, Throat and Ear , Philadelphia, W. B. Saunders Company, 1945;, p. 243.
7 +
Bifulco, E.:  Pulmonary Bacillus Pyocyaneus (Pseudomonas Aeruginosa) Infection in and Adult with Recovery , New York J. Med. 49:1195 ( (May 15) ) 1949;.

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