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June 1951, Vol 81, No. 6 >
Article | June 1951

ISOPROPANOL ADMINISTERED RECTALLY FREE

ARTHUR J. NEWMAN, M.D.
AMA Am J Dis Child. 1951;81(6):798-800. doi:10.1001/archpedi.1951.02040030812007.
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ORAL ingestion of isopropyl alcohol is not unknown, and deaths due to its ingestion are occasionally encountered. A fair amount of investigation of the pharmacological properties of this aliphatic alcohol has been done in animals but clinical reports have not been forthcoming, and only one article1 has been encountered in the literature which reports cases of poisoning due to isopropyl alcohol.

During the past war the use of isopropyl alcohol instead of ethyl alcohol for certain medicinal purposes was begun. In addition to its use as disinfectant, it has been widely used as rubbing alcohol. Preparations for this purpose consist of 70 to 85 per cent isopropyl alcohol with a minute amount of perfume and the remainder water.

Both because of the paucity of literature on this subject and because of the unusual method of administration of the drug in this instance, it was thought advisable to publish this

REFERENCES

1 +
McCord, W. M.; Switzer, P. K., and Brill, H. H., Jr.:  Isopropyl Alcohol Intoxication , South. M. J. 41:639, 1948;.
2 +
Morris, H. J., and Lightbody, H. D.:  Toxicity of Isopropanol , J. Indust. Hyg. & Toxicol. 20:428, 1938;.
3 +
Lehman, A. J., and Chase, H. F.:  The Acute and Chronic Toxicity of Isopropyl Alcohol , J. Lab. & Clin. Med. 29:561, 1944;.
4 +
Kemal, H.:  Contribution to the Fate of Isopropyl Alcohol in the Human Organism , Biochem. Ztschr. 187:461, 1927;.
5 +
Chu, N.; Driver, R. L., and Hanzlik, P. J.:  Anticonvulsant Action of Isopropyl Alcohol , J. Pharmacol. & Exper. Therap. 92:291, 1948;.
6 +
Weese, H.:  A Comparative Study on the Efficiency and Toxicity of Vapors of the Lower Aliphatic Alcohols , Arch. exper. Path. u. Pharmakol. 135:118, 1928;.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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References

1 +
McCord, W. M.; Switzer, P. K., and Brill, H. H., Jr.:  Isopropyl Alcohol Intoxication , South. M. J. 41:639, 1948;.
2 +
Morris, H. J., and Lightbody, H. D.:  Toxicity of Isopropanol , J. Indust. Hyg. & Toxicol. 20:428, 1938;.
3 +
Lehman, A. J., and Chase, H. F.:  The Acute and Chronic Toxicity of Isopropyl Alcohol , J. Lab. & Clin. Med. 29:561, 1944;.
4 +
Kemal, H.:  Contribution to the Fate of Isopropyl Alcohol in the Human Organism , Biochem. Ztschr. 187:461, 1927;.
5 +
Chu, N.; Driver, R. L., and Hanzlik, P. J.:  Anticonvulsant Action of Isopropyl Alcohol , J. Pharmacol. & Exper. Therap. 92:291, 1948;.
6 +
Weese, H.:  A Comparative Study on the Efficiency and Toxicity of Vapors of the Lower Aliphatic Alcohols , Arch. exper. Path. u. Pharmakol. 135:118, 1928;.

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