We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
The Pediatric Forum |

Laboratory Testing for Drug Abuse

Elizabeth A. Warner, MD; Peter D. Friedmann, MD
Arch Pediatr Adolesc Med. 2006;160(8):854. doi:10.1001/archpedi.160.8.854-a.
Text Size: A A A
Published online


The Levy et al article1 on adolescent physicians' knowledge of the practices of screening for drug abuse is timely. We have long felt that practicing physicians' knowledge of drug testing has not recognized the technical and ethical issues involved.2 In our experience, clinical testing for drug abuse does not follow the policies and procedures outlined for federal workplace testing. In fact, most hospital laboratories do not have established policies for validation of specimens and many do not have the ability to perform confirmatory testing, which in federal testing requires gas chromatography/mass spectroscopy. We disagree with the blanket statement of Levy et al that urine drug screenings do not detect oxycodone and ecstasy (3,4-methylenedioxymethamphetamine). The ability to detect these substances depends on the cross-reactivity of the particular immunoassay used. The technology for immunoassays is continually evolving and many of the currently used assays do, in fact, detect these substances. Physicians who order drug screens can review the package inserts provided to the laboratory by the manufacturer of the immunoassay to determine the sensitivity of the assay for detecting oxycodone, ecstasy, and other specific substances.3 Another important question, which the authors did not address, is whether the physicians obtain informed consent before performing laboratory screening for drug abuse.

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
PubMed Articles