0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
This Month in Archives of Pediatrics and Adolescent Medicine |

This Month in Archives of Pediatrics & Adolescent Medicine FREE

Arch Pediatr Adolesc Med. 2009;163(10):878. doi:10.1001/archpediatrics.2009.189.
Text Size: A A A
Published online

PREGNANCY OUTCOMES IN FEMALE CHILDHOOD AND ADOLESCENT CANCER SURVIVORS: A LINKED CANCER-BIRTH REGISTRY ANALYSIS

One concern of female childhood and adolescent cancer survivors is the possibility of adverse outcomes among their offspring. Using data from 4 US regions, Mueller and colleagues conducted a population-based study to compare the occurrence of infancy outcomes among offspring of female cancer survivors with a comparison group identified from birth records. The proportion of childhood cancer patients identified with live births ranged from 13% to 17% across the 4 regions, with an overall mean time from diagnosis to delivery of 8.5 years. Infants of childhood cancer survivors were more likely to be born preterm and to weigh less than 2500 g. There was no increased risk of birth malformations or infant death.

See Article

SELECTIVE SEROTONIN REUPTAKE INHIBITOR EXPOSURE IN UTERO AND PREGNANCY OUTCOMES

This study sought to investigate the association between selective serotonin reuptake inhibitor (SSRI) intake, a history of psychiatric disease, and pregnancy outcomes in a Danish cohort of 57 001 pregnancies. There was no association of SSRI exposure during pregnancy with birth weight or head circumference. However, infants exposed to SSRIs were more likely to have a 5-minute Apgar score of less than 8 and were more likely to be admitted to the neonatal intensive care unit. The results corroborate earlier studies with less control for the potential effects of the underlying disease. However, treatment of depression during pregnancy may be warranted and future studies need to distinguish between individual SSRIs to find the safest medication.

See Article

A LONGITUDINAL STUDY OF MATERNAL DEPRESSION AND CHILD MALTREATMENT IN A NATIONAL SAMPLE OF FAMILIES INVESTIGATED BY CHILD PROTECTIVE SERVICES

Maternal depression is common and it is associated with a 2- to 3-fold increased risk of perpetrating physical child abuse, psychological aggression, and medical neglect. This study used longitudinal data collected from a nationally representative sample of more than 2000 families investigated for maltreatment to examine whether change in depression status predicts change in maltreatment. More than one-third of mothers experienced the onset or remission of depression during the 3-year follow-up. Change in a mother's depression status was associated with a change in the number of psychologically aggressive acts toward her child, but it was not associated with a change in physical assault or neglect. These findings suggest that reducing maternal depression may reduce children's exposure to psychological aggression. Effective programs to treat maternal depression must be developed and implemented.

See Article

CHARACTERISTICS AND CONCORDANCE OF AUTISM SPECTRUM DISORDERS AMONG 277 TWIN PAIRS

While only 10% of autism spectrum disorder (ASD) cases can be directly attributed to an underlying medical condition, the etiologies of idiopathic autism are likely a combination of genetic and environmental contributions. This study examined 277 twin pairs in which at least 1 twin was affected by ASD. Concordance for ASD was significantly higher among monozygotic than dizygotic twins (88.1% vs 30.5%). Autism syndrome and pervasive developmental delay may be inherited differently, since concordant monozygotic twins were much less likely to have the same severity of ASD. This cross-sectional study represents the largest collection of twins with at least 1 ASD-affected sibling, culled from a US online autism registry.

Place holder to copy figure label and caption

Lag in autism spectrum disorder (ASD) diagnosis among concordant twin pairs, dizygotic (DZ) (n = 32) vs monozygotic (MZ) (n = 29).

Graphic Jump Location

See Article

Figures

Place holder to copy figure label and caption

Lag in autism spectrum disorder (ASD) diagnosis among concordant twin pairs, dizygotic (DZ) (n = 32) vs monozygotic (MZ) (n = 29).

Graphic Jump Location

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

135 Views
0 Citations
×

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs