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Elevated Circulating Estradiol Level in Neonatal Ovarian Cyst

Osamu Arisaka, MD; Sanae Kanazawa, MD; Mariko Ohyama, MD; Akihisa Nitta, MD; Hiroshi Suzumura, MD; Takeo Kuribayashi, MD
Arch Pediatr Adolesc Med. 1999;153(11):1202-1203. doi:.
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In their recent report, Hamrick and Fordham1 provided reassurance that neonatal ovarian cyst (OC) can be managed in pediatric practice. They nicely illustrated the diagnosis and treatment of a patient with OC, which was detected because of an abdominal mass and associated clinical symptoms. In addition to familiar clinical issues related to neonatal OC, mainly aspects of surgical management, we would like to add here another clinical aspect of the management of OC, that of endocrinology.

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Changes in the serum estradiol levels in 5 infants with ovarian cysts during the follow-up period. The shaded area indicates the normal range (less than ±2 SDs) measured in control subjects. Arrow indicates the timing of cyst aspiration.

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