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Commentary |

A Commentary on the Use of Rational Oral Electrolyte Therapy

Laurence Finberg, MD
Arch Pediatr Adolesc Med. 1999;153(9):910-912. doi:10.1001/archpedi.153.9.910.
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The following dissertation is derived partially from the literature, is partially a personal memoir, and contains a speculation. I try to answer the question of why oral glucose-electrolyte therapy was so long delayed as a part of the therapeutic armamentarium and why the present formulation of rehydration solutions has taken so long to gain acceptance in the United States. The story begins 268 years ago.

Harvey  W Exercitatio Anatomica de Motu Cordis et Sanguinis in Animalibus [The Circulation of the Blood and Other Writings]. Frankin  KWear  Atrans-eds London, England JM Dent & Sons Ltd1990;
O'Shaughnessy  WB Experiments on blood in cholera. Lancet. 1831-1832;1490
Latta  T Affording view of the rationale and results of his practice in treatment of cholera and saline injections [letter]. Lancet. 1831-1832;2274
Cantini  A A cholera benhandlung. Berl Klin Weknschr. 1892;29914- 924Friis-Hansen  BNichols  BLBallabrigia  AKretchmer  NHistory of Pediatrics. New York, NY Raven Press1991;257- 266Nestle Nutritional Workshop Series.
Sellards  AW The tolerance for alkalies in Asiatic cholera. Philippine J Sci. Sect B.1910;5363
Rogers  L The mortality from post-choleraic uremia: a 70% reduction through intravenous injection of sodium bicarbonate. Lancet. 1917;193745
Link to Article[[XSLOpenURL/10.1016/S0140-6736(00)53982-8]]
Govan  CD  JrDarrow  DC The use of potassium chloride in the treatment of the dehydration of diarrhea in infants. J Pediatr. 1946;28541- 549
Link to Article[[XSLOpenURL/10.1016/S0022-3476(46)80214-2]]
Colle  EAyoub  ERaile  R Hypertonic dehydration (hypernatremia): the role of feedings high in solute. Pediatrics. 1958;225
Shultz  SGFrizzell  RANellans  HN Ion transport by mammalian small intestine. Ann Rev Physiol. 1974;3651- 91
Link to Article[[XSLOpenURL/10.1146/annurev.ph.36.030174.000411]]
Philips  RW Water and electrolyte losses in cholera. Fed Proc. 1964;23705

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