We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Comment & Response |

DRD4, Income, and Children’s Food Choices Plasticity Allele or Different Opportunities?

Vivian Yeo, MD1; Alison Poulton, MBBChir, MD, FRACP1; Anu Ashokan, MBBS, DCH1
[+] Author Affiliations
1Nepean Hospital, New South Wales, Australia
JAMA Pediatr. 2016;170(8):810. doi:10.1001/jamapediatrics.2016.1040.
Text Size: A A A
Published online


To the Editor We read with great interest the article “Genetic Differential Susceptibility to Socioeconomic Status and Childhood Obesogenic Behavior: Why Targeted Prevention May Be the Best Societal Investment,” by Silveira et al.1 In this study, the authors found that girls carrying the 7-repeat allele of DRD4 who were from a low-income bracket had increased fat intake compared with noncarriers. Similarly, girls carrying the 7-repeat allele of DRD4 who were from families with a higher income bracket had decreased fat intake compared with noncarriers. The authors postulated that the 7-repeat allele of DRD4 might not simply indicate increased susceptibility to obesity but actually be a plasticity allele that might be advantageous in more favorable settings but obesogenic in adversity.


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





August 1, 2016
Patrícia P. Silveira, MD, PhD; Michael J. Meaney, PhD, CQ, FRSC; Laurette Dubé, BSc, MBA, MPS, PhD
1Department of Pediatrics, Faculty of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
2Ludmer Centre for Neuroinformatics and Mental Health, Douglas Mental Health University Institute, McGill University, Montreal, Quèbec, Canada3Douglas Mental Health University Institute, Montreal, Quèbec, Canada
4Desautels Faculty of Management, McGill Center for the Convergence of Health and Economics, McGill University, Montreal, Quebec, Canada
JAMA Pediatr. 2016;170(8):810-811. doi:10.1001/jamapediatrics.2016.1043.
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...