Accepted for Publication: February 24, 2015.
Published Online: July 6, 2015. doi:10.1001/jamapediatrics.2015.0498.
Study concept and design: Tiemeier, Peeters, Hofman, Verhulst, Ghassabian.
Acquisition, analysis, or interpretation of data: Modesto, Tiemeier, Peeters, Jaddoe, Verhulst, Ghassabian.
Drafting of the manuscript: Modesto, Ghassabian.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Modesto, Tiemeier, Ghassabian.
Obtained funding: Tiemeier, Jaddoe.
Study supervision: Tiemeier, Peeters, Hofman, Verhulst, Ghassabian.
Conflict of Interest Disclosures: Dr Verhulst is the contributing editor of the Achenbach System of Empirically Based Assessment, from which he receives remuneration. No other disclosures were reported.
Funding/Support: The Generation R Study is supported by the Erasmus Medical Center, Rotterdam; Erasmus University Rotterdam; Netherlands Organization for Health Research and Development; Netherlands Organisation for Scientific Research; Ministry of Health, Welfare, and Sport; and Ministry of Youth and Families. Measurements of thyroid hormone levels have been made possible by a generous financial gift from Ortho Clinical Diagnostics and Jan Dekker/Ludgardine Bouwman Foundation, Fa Merck, and Foundation Zeist. This study was also supported by research grant FP7/2008–2013 from the European Community’s Seventh Framework Programme under grant agreement 212652 (NUTRIMENTHE project, The Effect of Diet on the Mental Performance of Children) (Drs Tiemeier and Ghassabian).
Role of the Funder/Sponsor: The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: We thank the general practitioners, hospitals, midwives, and pharmacies in Rotterdam who contributed to this study.