Accepted for Publication: March 3, 2015.
Published Online: May 4, 2015. doi:10.1001/jamapediatrics.2015.0636.
Study concept and design: Powers, Stark, Chamberlin, Brody, Castile, Stallings.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Powers, Stark, Chamberlin, Filigno, Szczesniak, Rausch, Clancy.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Powers, Chamberlin, Szczesniak, Rausch.
Obtained funding: Powers, Chamberlin, Stallings.
Administrative, technical, or material support: Powers, Chamberlin, Filigno, Sullivan, Butcher, Brody, Schindler, Konstan, Nasr, Castile, Acton, Ksenich, Clancy.
Study supervision: Powers, Stark, Chamberlin, Filigno, Sullivan, Lemanek, McCoy, Castile, Acton, Stallings.
Conflict of Interest Disclosures: None reported.
Funding/Support: Funding for the Families Understanding Nutrition Study was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (grants R01 DK054915-06A1; principal investigator [PI]: Dr Powers and NOT-OD-09-056; PI: Dr Powers), the Cystic Fibrosis Foundation Therapeutics Inc (05A0; PI: Dr Powers). The Families Understanding Nutrition Study was supported by the National Institutes of Health Cystic Fibrosis Core Center (grant P30 DK 27651; PI: Dr Konstan), National Center for Advancing Translational Sciences of the National Institutes of Health (grant UL1TR000077; PIs: James Heubi, MD, and Joel Tsevat, MD, MPH), and, for some of the postdoctoral fellows who contributed to the trial, the National Institute of Diabetes and Digestive and Kidney Diseases (grant T32DK063929; program director: Dr Powers).
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Disclaimer: This content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Diabetes and Digestive and Kidney Diseases or the National Institutes of Health.
Additional Contributions: We thank all of the children and families who participated in this clinical trial. The members of the Families Understanding Nutrition Study Group are as follows: National Institute of Diabetes and Digestive and Kidney Diseases Program Officer: C. McKeon, PhD; Cystic Fibrosis Foundation Data Safety Monitoring Board: M. Schechter, MD, MPH, D. Borowitz, MD, S. Murray, ScD, and M. Hunt-Bennett; Clinical Coordinating Center, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio: J. Allen, MS, CCRP, K. Barnett, BS, J. Bean, PhD, E. Brannon, BS, D. Buckley, MEd, M. Crawford Cohen, PhD, E. Dunlap, BA, R. Henry, BA, H. Kalkwarf, RD, PhD, J. Kroner, BA, S. Morgan, BS, S. Rieck, RD, C. Shenk, PhD, A. Shova, RD, M. Somers, MS, and S. Summer, MS, RD; Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio: L. Cittadino, RD, G. McPhail, MD, S. Morgan, BS, S. Saltarelli, RD, and L. Williams, PhD, CF Care Team; Nationwide Children’s Hospital, Columbus, Ohio: S. Gemma, RD, D. Gilman, PhD, K. Guilfoyle, BA, T. Johnson, RN, A. King, PsyD, E. Clough-Paabo, BA, A. Rice, RD, and J. Richdale-Robb, RD, CF Care Team; Rainbow Babies and Children’s Hospital–University Hospitals Case Medical Center, Cleveland, Ohio: C. Bucur, RN, R. Hazen, PhD, K. Hilliard, BA, and J. Lee, RN, CF Care Team; University of Michigan, Ann Arbor: M. Myrvik, PhD, and M. O’Leary, RD, CF Care Team; University of Arizona, Tucson: O. Molina, BS, and P. Settle, MS, RD, CF Care Team; Akron Children’s Hospital, Akron, Ohio: N. Kraynack, MD, D. Ouellette, RN, and S. Phillips, MS, RD, CF Care Team; and Children’s Medical Center of Dayton, Dayton, Ohio: S. Bartosik, RN, and R. Fink, MD, CF Care Team. These members received salary support from the National Institutes of Health and the Cystic Fibrosis Foundation.