We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Comment & Response |

Placebo Effects in Infants, Toddlers, and Parents

Luana Colloca, MD, PhD1,2
[+] Author Affiliations
1Department of Pain and Translational Symptom Science, School of Nursing, University of Maryland, Baltimore
2Department of Anesthesiology, School of Medicine, University of Maryland, Baltimore
JAMA Pediatr. 2015;169(5):504-505. doi:10.1001/jamapediatrics.2014.3795.
Text Size: A A A
Published online


To the Editor Paul and colleagues1 studied 120 infants and toddlers aged 2 to 47 months with acute cough. Infants and toddlers were randomized to pasteurized agave nectar mixed with natural grape flavoring and other bulking agents, natural grape-flavored water with caramel color (placebo), and a no treatment group.1 Significant symptom improvements were found for the agave nectar and placebo groups compared with the no treatment group, with no significant differences for any outcome between the agave nectar and placebo groups.1


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





May 1, 2015
Joe Kossowsky, PhD; Ted J. Kaptchuk, OMD
1Department of Anesthesiology, Perioperative, and Pain Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts
2Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts
JAMA Pediatr. 2015;169(5):505. doi:10.1001/jamapediatrics.2014.3798.
May 1, 2015
Ian M. Paul, MD, MSc
1Division of Academic General Pediatrics, Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania
JAMA Pediatr. 2015;169(5):505-506. doi:10.1001/jamapediatrics.2014.3801.
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...