We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
The Pediatric Forum |

Neonatal Hypermagnesemia: More Causes and More Symptoms

Hassib Narchi, MD, FRCP, FRCPCH
Arch Pediatr Adolesc Med. 2001;155(9):1074. doi:10.1001/archpedi.155.9.1072.
Text Size: A A A
Published online


I read with interest the report of hypermagnesemia in a 4-week-old infant caused by magnesium hydroxide administration.1 Other causes of neonatal hypermagnesemia mentioned by the authors include administration of intravenous magnesium sulfate to the mother for eclampsia and magnesium-containing laxatives or antacids to the infant. I would like to add previously undescribed manifestations and causes of neonatal hypermagnesemia reported in a premature neonate who developed delayed intestinal transit and arrhythmias following the erroneous administration of intramuscular magnesium sulfate for hypomagnesemia prior to transfer to our institution.2 Increased gastric residue with mild abdominal distension and delayed passage of meconium for several days were the main features with few episodes of premature ventricular contraction, which resolved spontaneously within a few days. The serum magnesium level was 3.3 mg/dL (1.4 mmol/L). The mother did not have a history of magnesium sulfate therapy before delivery. Investigations revealed that although the infant was prescribed a dose of 0.8 mEq/L of magnesium (equivalent to 0.4 mmol of magnesium per liter or 0.2 mL of 50% magnesium sulfate) intramuscularly prior to the transfer, the injected dose was 0.8 mL (instead of 0.8 mEq/L) of 50% magnesium sulfate, or 4 times the prescribed dose. Serum magnesium levels progressively declined during a 10-day period and regular intestinal transit was established by the end of the second week.


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

1 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.