Accepted for Publication: June 24, 2014.
Published Online: September 22, 2014. doi:10.1001/jamapediatrics.2014.1392.
Study concept and design: Sigal, Goldfield, Prud’homme, Hadjiyannakis, Gougeon, Wells, Kenny.
Acquisition, analysis, or interpretation of data: Sigal, Alberga, Goldfield, Prud’homme, Gougeon, Phillips, Tulloch, Malcolm, Doucette, Ma, Kenny.
Drafting of the manuscript: Sigal, Alberga, Kenny.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Doucette, Wells, Ma.
Obtained funding: Sigal, Goldfield, Prud’homme, Hadjiyannakis, Gougeon, Wells, Kenny.
Administrative, technical, or material support: Sigal, Alberga, Phillips, Malcolm, Kenny.
Study supervision: Sigal, Alberga, Goldfield, Prud’homme, Kenny.
Conflict of Interest Disclosures: None reported.
Funding/Support: The HEARTY trial was supported by grant MCT-71979 from the Canadian Institutes of Health Research. Dr Sigal is supported by a Health Senior Scholar award from Alberta Innovates–Health Solutions and was previously supported by a Research Chair from the Ottawa Hospital Research Institute during part of this trial. Dr Alberga was supported by a Doctoral Student Research Award from the Canadian Diabetes Association. Dr Goldfield was supported by a New Investigator Award from the Canadian Institutes of Health Research for part of the trial and subsequently by an Endowed Research Scholarship from the Children’s Hospital of Eastern Ontario Volunteer Association Board. Dr Kenny was supported by a University Research Chair from the University of Ottawa.
Role of Funder/Sponsor: The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: We thank the HEARTY trial participants. Krista Hind, BSc (deceased), Bruno Lemire, PhD, Marta Wein, BSc, Kim Robertson, BSc, Kim Fetch, BSc, Brittany Hanlon, MHA, Jane Yardley, PhD, Nadia Balaa, BSc, Karen Lopez, BSc, Pamela Martino, MSc, Kim Morin, BSc, Colleen Gilchrist, BSc, RD, Pascale Messier, BSc, RD, Kelley Phillips, MA, and students in the School of Human Kinetics, University of Ottawa, who contributed to study coordination, exercise training, and evaluation of study participants. Robert Ross, PhD (Queens University, Kingston, Ontario, Canada), Alison Bradshaw, MSc, and Jennifer Kuk, PhD (York University, Toronto, Ontario, Canada), and Yves Martel, PhD (Tomovision, Magog, Quebec, Canada) assisted with training and provided ongoing advice on body composition analysis. The Ottawa-Carleton Regional YMCA/YWCA (Ottawa, Ontario, Canada), RA Centre (Ottawa, Ontario, Canada), Children’s Hospital of Eastern Ontario, and Nautilus Plus and MRI Plus (both in Gatineau, Quebec, Canada) collaborated throughout the trial. Robert Ross, PhD, received financial compensation beyond his usual salary.
Correction: This article was corrected on June 25, 2015, to fix an SD value in Table 1.