Accepted for Publication: February 11, 2014.
Published Online: June 30, 2014. doi:10.1001/jamapediatrics.2014.332.
Study concept and design: J. Liu, X. Liu.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: J. Liu, X. Liu, W. Wang, Y. Wang, Li.
Critical revision of the manuscript for important intellectual content: J. Liu, X. Liu, McCauley, Pinto-Martin, Li, Yan, Rogan.
Statistical analysis: J. Liu, X. Liu, W. Wang, Y. Wang, Rogan.
Obtained funding: J. Liu.
Administrative, technical, or material support: Y. Wang, Li, Yan.
Study supervision: J. Liu, X. Liu, McCauley, Pinto-Martin.
Conflict of Interest Disclosures: None reported.
Funding/Support: This work was supported by National Institute of Environmental Health Sciences grants R01-ES018858, K01-ES015877, K02-ES019878, and P30-ES013508; the University of Pennsylvania Center of Excellence in Environmental Toxicology; the Wacker Foundation; the Jintan city government; and Jintan Hospital. Dr Rogan was supported by the Intramural Research Program at the National Institute of Environmental Health Sciences.
Role of the Sponsor: The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: Thanks are extended to the children, their families, and the research team (Liping Zhang, MD, Erda Liu, MD, Yuexian Ai, BS, RN, and Liudi Han, BS, RN) from the China Jintan Cohort Study Group. We are very grateful to the Jintan Hospital, the Jintan Maternal-Child Health Center, and the Jintan city government for their support and assistance. Rebecca Loh, BA, and Siyuan Cao, BA, BS, served as research assistants in this study; Xiaoming Shen, PhD, provided an early contribution during blood lead analysis; and Dr Shen and Herbert Needleman, PhD, provided instrumental support for the Jintan lead study. There was no financial compensation for these services.