THE YEAR 1946 marked the twenty-fifth anniversary of the discovery of insulin. It seemed appropriate, therefore, to review the records of the Hospital for Sick Children in an attempt to learn the present condition of the patients with juvenile diabetes who had been treated here. Similar reports have been made from other clinics.1
It was decided to limit the study to those patients who had had the disease for at least fifteen years. The record, therefore, includes those patients who were still alive in 1922, when insulin became available,, and all those in whom the disease developed prior to 1932. This gathering of data necessitated a rather extensive follow-up program, since the hospital cares for patients only to the age of 14 years.
The majority of the patients were traced and were requested to attend the hospital clinic or, if unable to do so, to fill out a questionnaire.