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CLINICAL ADEQUACY OF A SINGLE MEASUREMENT OF VITAMIN A ABSORPTION

EDWARD L. PRATT, M.D.; KATHLEEN R. FAHEY, A.B.
Am J Dis Child. 1944;68(2):83-85. doi:10.1001/archpedi.1944.02020080003001.
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The measurement of the rate of absorption of vitamin A has proved to be of value in the study of patients with chronic disturbances of nutrition. Empirically it has been found to be useful in the study of these patients, even though it may be influenced by several factors besides the intestinal absorption of fat.1 However, the time consumed in making the numerous determinations and the difficulty in obtaining several consecutive samples of venous blood from small infants has limited the usefulness of the test.

The following study, based on the curves for the rate of absorption of vitamin A for 112 patients, aged 4 weeks to 12 years, was made in order to determine the feasibility of simplifying the procedure. This study reveals that for patients in this particular age group a single determination of vitamin A and carotenoids in the blood made at an appropriate interval after

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