This report was based on the study of fifty instances of thrombosis of the intracranial venous sinuses in infancy and in childhood. We have endeavored to correlate the clinical histories, laboratory data and postmortem studies. An attempt has been made to emphasize a large group of cases to which no definite etiology was assigned. The lesions of the brain consequent to thrombosis of the sinuses and their bearing on neurologic disturbances have been discussed.
One of the first descriptions of a probable instance of sinus thrombosis was written by Morgagni (1717).1 The first accurate study of the condition has been attributed to Abercrombie.2 In the latter part of the nineteenth century French physicians reported many instances. Bouchut3 observed thirty cases in twenty-three years. He concluded that thrombosis of the dural sinuses was often found in infants who had convulsions for the first time during the