Accepted for Publication: October 17, 2013.
Published Online: April 22, 2013. doi:10.1001/jamapediatrics.2013.1206
Author Contributions: Dr Lipshultz had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Lipshultz, Williams, Wilkinson, Van Dyke, Shearer, Rich, and Hazra. Acquisition of data: Van Dyke, Dooley, Scott, and Colan. Analysis and interpretation of data: Lipshultz, Williams, Wilkinson, Leister, Van Dyke, Shearer, Rich, Hazra, Kaltman, Jacobson, Rabideau, and Colan. Drafting of the manuscript: Lipshultz, Williams, Wilkinson, Rich, Kaltman, Dooley, and Rabideau. Critical revision of the manuscript for important intellectual content: Lipshultz, Williams, Wilkinson, Leister, Van Dyke, Shearer, Rich, Hazra, Kaltman, Jacobson, Scott, and Colan. Statistical analysis: Williams, Leister, Shearer, and Jacobson. Obtained funding: Williams, Van Dyke, and Rich. Administrative, technical, and material support: Lipshultz, Wilkinson, Shearer, Rich, Kaltman, Dooley, Rabideau, and Colan. Study supervision: Lipshultz, Williams, Wilkinson, Van Dyke, Hazra, and Kaltman.
PHACS Group Members: The following institutions, clinical site investigators, and staff participated in conducting PHACS AMP in 2012: William Shearer, Mary Paul, Norma Cooper, and Lynette Harris (Baylor College of Medicine, Houston, Texas); Murli Purswani, Mahboobullah Baig, and Anna Cintron (Bronx Lebanon Hospital Center, New York); Ana Puga, Sandra Navarro, Doyle Patton, and Deyana Leon (Children's Diagnostic and Treatment Center, Fort Lauderdale, Florida); Sandra Burchett, Nancy Karthas, and Betsy Kammerer (Boston Children's Hospital, Massachusetts); Ram Yogev, Margaret Ann Sanders, Kathleen Malee, and Scott Hunter (Ann and Robert H. Lurie Children's Hospital of Chicago, Illinois); Andrew Wiznia, Marlene Burey, and Molly Nozyce (Jacobi Medical Center, Bronx, New York); Janet Chen, Latreca Ivey, Maria Garcia Bulkley, and Mitzie Grant (St Christopher's Hospital for Children, Philadelphia, Pennsylvania); Katherine Knapp, Kim Allison, and Megan Wilkins (St Jude Children's Research Hospital, Chicago, Illinois); Midnela Acevedo-Flores, Heida Rios, and Vivian Olivera (San Juan Hospital/Department of Pediatrics, Puerto Rico); Margarita Silio, Medea Jones, and Patricia Sirois (Tulane University Health Sciences Center, New Orleans, Louisiana); Stephen Spector, Kim Norris, and Sharon Nichols (University of California, San Diego); Elizabeth McFarland, Emily Barr, and Robin McEvoy (University of Colorado Denver Health Sciences Center); Arry Dieudonne, Linda Bettica, and Susan Adubato (University of Medicine and Dentistry of New Jersey, Newark); and Gwendolyn Scott, Patricia Bryan, and Elizabeth Willen (University of Miami, Florida).
Conflict of Interest Disclosures: None reported.
Funding/Support: The study and PHACS were supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development with cofunding from the National Institute on Drug Abuse, the National Institute of Allergy and Infectious Diseases, the Office of AIDS Research, the National Institute of Mental Health, the National Institute of Neurological Disorders and Stroke, the National Institute on Deafness and Other Communication Disorders, the National Heart, Lung, and Blood Institute, the National Institute of Dental and Craniofacial Research, and the National Institute on Alcohol Abuse and Alcoholism, through cooperative agreements with the Harvard School of Public Health (grants HD052102, 3 U01 HD052102-05S1, and 3 U01 HD052102-06S3) and the Tulane University School of Medicine (grants HD052104 and 3U01HD052104-06S1). Data management services were provided by the Frontier Science and Technology Research Foundation, and regulatory services and logistical support were provided by Westat, Inc.
Role of the Sponsors: Representatives of the National Institutes of Health were part of the study team, and therefore the sponsor was involved in the design and conduct of the study; in the collection, analysis, and interpretation of the data; and in the preparation, review, or approval of the manuscript.
Disclaimer: The conclusions and opinions expressed in this article are those of the authors and do not necessarily reflect those of the National Institutes of Health or the US Department of Health and Human Services.
Additional Contributions: We thank the children and families for their participation in PHACS and the individuals and institutions involved in the conduct of PHACS.