0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
The Pediatric Forum |

Genetic Risk in Childhood Obesity: Implications for Clinical Practice

Robert P. Young, BMedSc, MBChB, DPhil, FRACP, FRCP; Raewyn J. Hopkins, BN, MPH
JAMA Pediatr. 2013;167(2):196-198. doi:10.1001/2013.jamapediatrics.252.
Text Size: A A A
Published online

Extract

We wish to comment on the recently published editorial by Fernandez1 in relation to an article by Belsky et al2 that validates a gene-based risk tool for obesity in a birth cohort followed up prospectively.

First, given the steeply rising rates of obesity over the last few decades, it is clear that changes in lifestyle (ie, the environment) are “pivotal” to the development of obesity.1 While the genes underlying obesity have been present for centuries, it is their effect that has recently emerged in societies where “lifestyle” has dramatically changed. This means regardless of genetic predisposition, there need be no concern about “genetic determinism” in the public health community. Instead there should be enthusiasm for the potential to identify those at greatest risk for targeted and cost-effective interventions. This must be preferable to (over)generalized health messages that are inconsequential for the wider population. The best example of the success of the targeted approach comes from the enormous drop in death rates from coronary artery disease following several decades of cholesterol-lowering treatment (see later).

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

February 1, 2013
Jose R. Fernandez, PhD
JAMA Pediatr. 2013;167(2):196-198. doi:10.1001/2013.jamapediatrics.255.
CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Articles Related By Topic
Related Collections
PubMed Articles
Jobs
brightcove.createExperiences();