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Predicting Postconcussion Syndrome After Mild Traumatic Brain Injury in Children and Adolescents Who Present to the Emergency Department

Lynn Babcock, MD, MS; Terri Byczkowski, PhD; Shari L. Wade, PhD; Mona Ho, MS; Sohug Mookerjee, BS, MPH; Jeffrey J. Bazarian, MD, MPH
JAMA Pediatr. 2013;167(2):156-161. doi:10.1001/jamapediatrics.2013.434.
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Objective  To determine the acute predictors associated with the development of postconcussion syndrome (PCS) in children and adolescents after mild traumatic brain injury.

Design  Retrospective analysis of a prospective observational study.

Setting  Pediatric emergency department (ED) in a children's hospital.

Participants  Four hundred six children and adolescents aged 5 to 18 years.

Main Exposure  Closed head trauma.

Main Outcome Measures  The Rivermead Post Concussion Symptoms Questionnaire administered 3 months after the injury.

Results  Of the patients presenting to the ED with mild traumatic brain injury, 29.3% developed PCS. The most frequent PCS symptom was headache. Predictors of PCS, while controlling for other factors, were being of adolescent age, headache on presentation to the ED, and admission to the hospital. Patients who developed PCS missed a mean (SD) of 7.4 (13.9) days of school.

Conclusions  Adolescents who have headache on ED presentation and require hospital admission at the ED encounter are at elevated risk for PCS after mild traumatic brain injury. Interventions to identify this population and begin early treatment may improve outcomes and reduce the burden of disease.

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Figure. Frequency and severity of postconcussion syndrome (PCS) symptoms for all children and adolescents with mild traumatic brain injury who completed follow-up (n = 406).

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