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Research Letters | Feb 2013

Multiethnic WHO Growth Charts May Not Be Optimal in the Screening of Disorders Affecting Height: Turner Syndrome as a Model

Antti Saari, MD; Ulla Sankilampi, MD, PhD; Leo Dunkel, MD, PhD

JAMA Pediatr. 2013;167(2):194-195. doi:10.1001/jamapediatrics.2013.436.

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In 2006, the World Health Organization (WHO) published multiethnic growth charts for children younger than 5 years compiled of growth data of 6669 infants from 6 different countries (the United States, Norway, Oman, Brazil, India, and Ghana).¹ Originally, the rationale for the construction of the multiethnic WHO standards stemmed from an earlier study² that reported nearly similar growth patterns in infants and children from diverse ethnic backgrounds when their physiological needs are met and the environment supports healthy development.

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Figure. Percentage of girls with Turner syndrome (TS) with height for age less than the third (A) or the first (B) percentile of either the Finnish (upper lines) or the World Health Organization (WHO) (lower lines) growth reference for all girls with TS (n = 124, solid lines) and those with an XO karyotype (n = 60, dashed lines).

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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Saari A, Sankilampi U, Dunkel L. Multiethnic WHO Growth Charts May Not Be Optimal in the Screening of Disorders Affecting Height: Turner Syndrome as a Model. JAMA Pediatr. 2013;167(2):194-195. doi:10.1001/jamapediatrics.2013.436.

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