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Results of a Multidisciplinary Treatment Program in 3-Year-Old to 5-Year-Old Overweight or Obese Children:  A Randomized Controlled Clinical Trial

Gianni Bocca, MD; Eva Corpeleijn, PhD; Ronald P. Stolk, PhD; Pieter J. J. Sauer, MD, PhD
Arch Pediatr Adolesc Med. 2012;166(12):1109-1115. doi:10.1001/archpediatrics.2012.1638.
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Objective  To assess the effects of a multidisciplinary intervention program for 3-year-old to 5-year-old overweight and obese children compared with a usual-care program.

Design  Randomized controlled clinical trial conducted from October 2006 to March 2008.

Setting  Groningen Expert Center for Kids with Obesity at Beatrix Children's Hospital, University Medical Center Groningen.

Participants  Seventy-five children (29 overweight, 46 obese) aged 3 to 5 years.

Intervention  A multidisciplinary intervention program vs a usual-care program. Anthropometry was performed and body composition was determined by bioelectrical impedance analysis and ultrasonography at the start and end of the 16-week program and 12 months after starting the intervention.

Main Outcome Measures  The actual weight reduction, change in body mass index (BMI, calculated as weight in kilograms divided by height in meters squared), BMI z score, body fat percentage, and visceral fat in the multidisciplinary intervention group compared with a usual-care group.

Results  At the end of the treatment program, children in the multidisciplinary intervention group showed a greater decrease in BMI, BMI z score, and waist circumference z score compared with children in the usual-care group. At 12 months, children in the intervention group showed greater decreases in BMI, BMI z score, waist circumference, and waist circumference z score compared with children in the usual-care group. Visceral fat showed a trend toward a higher decrease.

Conclusions  A multidisciplinary intervention program in 3-year-old to 5-year-old overweight and obese children had beneficial effects on anthropometry and body composition. The positive effects were still present 12 months after the start of the intervention.

Trial Registration  isrctn.org Identifier: ISRCTN47185691

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Figures

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Grahic Jump Location

Figure 1. Flow diagram of study group assignment and follow-up. T0 indicates baseline; T1, 16 weeks; T2, 12 months.

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Grahic Jump Location

Figure 2. Body mass index (BMI) z score (A), waist circumference (WC) z score (B), and visceral fat (C) in the multidisciplinary intervention group and usual-care group from baseline to 12 months after the start of the intervention.

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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