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Use of Diagnostic Tests in Adolescents With Essential Hypertension

Esther Y. Yoon, MD, MPH; Lisa Cohn, MS; Albert Rocchini, MD; David Kershaw, MD; Gary Freed, MD, MPH; Frank Ascione, PhD, PharmD; Sarah Clark, MPH
Arch Pediatr Adolesc Med. 2012;166(9):857-862. doi:10.1001/archpediatrics.2012.1173.
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Objective  To describe the use of diagnostic tests in adolescents with essential hypertension.

Design  Longitudinal analysis of administrative claims data.

Setting  Michigan Medicaid program during 2003 to 2008.

Participants  Adolescents with 3 or more years of Medicaid eligibility (≥11 months/y) who had a diagnosis of essential hypertension and 1 or more antihypertensive medication pharmacy claims.

Main Outcome Measures  We examined adolescents' echocardiogram use and compared it with electrocardiogram (EKG) and renal ultrasonography use. We examined timing of the 3 diagnostic tests in relation to the first pharmacy claim. We examined patient demographics and presence of obesity-related comorbidities.

Results  During 2003 to 2008, there were 951 adolescents with essential hypertension who had antihypertensive pharmacy claims; 24% (226) had echocardiograms; 22% (207) had renal ultrasonography; and 50% (478) had EKGs. Males (odds ratio [OR], 1.53; 95% CI, 1.06-2.21), younger adolescents (OR, 1.69; 95% CI, 1.17-2.44), those who had EKGs (OR, 5.79; 95% CI, 4.02-8.36), and those who had renal ultrasonography (OR, 2.22; 95% CI, 1.54-3.20) were more likely to obtain echocardiograms compared with females, older adolescents, and adolescents who did not have EKGs or renal ultrasonography.

Conclusions  Guideline-recommended diagnostic tests—echocardiograms and renal ultrasonography—were equally poorly used by adolescents with essential hypertension. Sex and age differences exist in the use of echocardiograms by adolescents with essential hypertension. The decision and choice of diagnostic tests to evaluate adolescents with essential hypertension warrant further study to understand the underlying rationale for those decisions and to determine treatment effectiveness.

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