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H. O. RUH, M.D.
Am J Dis Child. 1916;XI(4):281-290. doi:10.1001/archpedi.1916.04110100042005.
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Acrocephalosyndactylie (Apert), acrosphenodactylie (Maygrier) or acrocephalosyndactylism, was first described by Troquart1 in 1886. Since the first description there have been ten other cases noted, namely, those of Beno2 in 1886, Galippe and Magnan3 in 1892. Wheaton,4 two cases, in 1894, Dubrisay5 in 1898, Maygrier6 in 1898, Fournier7 in 1898, Camus8 in 1905, Davis9 in 1915, and Bertolotti and Boidi-Trotti10 in 1915. Two other cases of symmetrical syndactylism with pathological changes in the bones of the head have been described but the descriptions are not of sufficient exactness to allow a diagnosis to be made. These cases are those of Parham11 and Haultain.12

Apert,13 in 1906, described the condition at length, and later Sterling,14 in 1914, in a review of the trophic diseases, deformities and delayed development of the osseous system, collected and reported cases to date


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