The contribution which I have to make has to do with the action of the pars intermedia of the pituitary gland. These particular activities of the gland, from a therapeutic standpoint, have become apparent through a study of an abnormal child carried on for the past two and a half years by me, and previously by several physicians connected with the dispensary of the Babies' Hospital, including Drs. Kerley and Van Ingen.
The patient was seen first on Sept. 1, 1905, at the age of 3 years and 8 months, when a diagnosis of cretinism was made on a history that she did not walk nor talk and on the presence of coarse, thick hair, an open mouth, a lolling tongue, short thick thighs, a fontanel of 1½ by 1½ inches and a weight of 27½ pounds.
Given thyroid in small doses, she gained rapidly and steadily in weight and