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DYSENTERY DUE TO SULFONAMIDE-RESISTANT SHIGELLA SONNEI CONTROLLED WITH CHLOROMYCETIN®

MERLIN L. COOPER, M.D.; HELEN M. KELLER, M.S.
AMA Am J Dis Child. 1950;80(6):911-920. doi:10.1001/archpedi.1950.04040020926004.
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OVER a period of 10 days five of 28 children in one unit of the Children's Hospital became acutely ill with fever and severe diarrhea. This unit consisted of six small wards, of four and five cubicles each. These five children had been admitted to the hospital 8, 8, 9, 30 and 135 days previously because of some other condition not referable to the gastrointestinal tract. The five patients were in four wards of four cubicles each. Two patients were in the first and third cubicles in one ward; the three other patients were in three separate wards. According to the order in which intestinal symptoms developed in these patients, they had been in the hospital 30, 8, 135, 8 and 9 days.

Cultures taken of stools at the onset of symptoms were positive for Shigella sonnei. Each patient was isolated as soon as the result of the stool cultures

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