Meconium ileus, first described by Landsteiner in 1905, refers to the neonatal form of fibrocystic disease of the pancreas and presents the clinical picture of intestinal obstruction due to inspissation of meconium in the small bowel and, to a lesser degree, in the proximal portion of the colon. The condition is relatively rare, the disorder in the present patient being the only one so diagnosed at Duke Hospital among 450,520 patients and more than 5,600 autopsies.
A review of the literature has not been undertaken since this was done recently by Wiglesworth,1 whose excellent paper should be consulted by anyone interested in fibrocystic disease of the pancreas in general or meconium ileus in particular. The most significant contribution since the aforementioned review has been that of Baggenstoss, Power and Grindlay,2 whose work will be considered in the comment following the case report.
REPORT OF A CASE