Case Reports |


Am J Dis Child. 1950;79(6):1049-1056. doi:10.1001/archpedi.1950.04040011068006.
Text Size: A A A
Published online

The syndrome of Ehlers and Danlos apparently is a constitutional dyscrasia of the mesenchyma, characterized by specific manifestations in the skin, joints and subcutaneous tissue, often associated with other congenital defects.

Its history was initiated in 1899 when Ehlers reported on a patient to the Danish Dermatologic Society.1 With the turn of the century, Morris made an indefinite presentation of a similar patient at a meeting of the Old Dermatological Society of London.2 Six years later, in 1906, Hallopeau and Macé de Lépinay described the condition under the name of pseudodiabetic xanthoma.3 Shortly thereafter, Cohn defined the pattern quite as it is recognized today.4 In 1908, Danlos reviewed the case presented in 1906, recognized the unusual basic manifestations, corrected the misleading impressions given by the original authors in their descriptive title and, like Ehlers and Cohn, outlined the new syndrome.5 The first report on the


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.