This is a collection of sixteen papers presented at a conference on aureomycin held by the Division of Mycology of the Section on Biology of the New York Academy of Sciences. The subject is covered intensively, from a general discussion of the discovery and source of aureomycin to the results of its use in various infections. The pharmacologic aspects and the toxicity of the drug are covered in detail, as are various bacteriologic studies in vitro and in vivo. Methods for determination of the antibiotic levels in body fluids are discussed.
Experimental work indicates that aureomycin is effective against a wide range of micro-organisms, including both bacilli and cocci. It appears also, on the basis of preliminary reports, to be highly effective against certain viral and rickettsial infections. Rocky Mountain spotted fever seems to be especially susceptible. California Q fever has responded promptly in a preliminary series of cases, and