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Case Reports |

ASEPTIC MENINGITIS FOLLOWING IMMUNIZATION WITH DIPHTHERIA TOXOID

HYMAN B. STILLERMAN, M.D.
Am J Dis Child. 1948;76(3):331-333. doi:10.1001/archpedi.1948.02030030341006.
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THE OCCURRENCE of a neurologic complication during the course of immunization against diphtheria with toxoid is most unusual. A review of the literature revealed a report by Schioppa1 of a case of transitory paralysis of the palate following immunization with diphtheria toxoid. The present case is 1 in which aseptic meningitis occurred during immunization with diphtheria toxoid.

REPORT OF A CASE  B. A. was an 18 year old white nurse in training at another hospital. Her reaction to the Schick test was found to be positive; consequently, she was started on a course of immunization with diphtheria toxoid. Because of a strong reaction to the Moloney test, the course of immunization was begun cautiously. On Sept. 19, 1946, she received 0.05 cc. of toxoid, the inoculation being followed by a severe local reaction. Therefore, the second dose, seven days later, was not increased, and this time she had only

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