This book is a collection of five lectures given at the Bowman Gray School of Medicine. These lectures represent the results of Dr. Drinker's experiments in both animal and human pulmonary physiology. It is written in an easy style, making the book delightful reading. Dr. Drinker presents clearly the physiopathologic background for the development of pulmonary edema and the serious effects of anoxia. In his discussion, the clinical implications of the underlying disturbance are always kept to the fore, making it a valuable book for the clinician. The vicious circle of anoxia, pulmonary edema and anoxia, with its insidious onset and its attendant dangers, is vividly presented. The need for early use of oxygen in conditions of deprivation of oxygen and the methods of best administering it in various circumstances are given. The clinician will find in this book the physiologic basis for much that is known of oxygen therapy.