0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Other Articles |

USE OF CONTINUOUS CAUDAL ANALGESIA FOR CONTROL OF HYPERTENSION IN ACUTE NEPHRITIS

JAMES G. HUGHES, M.D.; GEORGE S. LOVEJOY, M.D.; HARVEY D. LYNN, M.D.; ROBERT A. HINGSON, M.D.
Am J Dis Child. 1948;75(3):291-308. doi:10.1001/archpedi.1948.02030020303003.
Text Size: A A A
Published online

THE MAJORITY of children with acute nephritis have arterial hypertension, which is generally considered to be due to widespread arteriolar spasm.1 The cause of this vasospasm may be renal ischemia, resulting in the production of excessive amounts of renin. According to this theory, the excessive amounts of renin act in the plasma on the angiotonin precursor to produce increased amounts of the active vasoconstrictor agent angiotonin, which incites the arteriolar spasm.

Excessive hypertension in persons with acute nephritis may be dangerous from two standpoints: 1. It may, possibly in conjunction with changes in the myocardial fibers, precipitate cardiac failure. 2. Severe vasospasm of cerebral vessels associated with the hypertension may produce anoxia of brain tissue and lead to the cerebral manifestations commonly called hypertensive encephalopathy. These manifestations may consist of restlessness, dimness of vision, sudden blindness, diplopia, headache, drowsiness, vomiting, and severe convulsions, resulting in death. Cerebral vasospasm, rather

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();