ARTERIAL EMBOLISM AND THROMBOSIS IN INFANCY

Arterial thrombosis and arterial embolism are well recognized entities in adult patients and have received extensive consideration in medical journals and textbooks. Little attention has, however, been paid to such vascular occlusions in young subjects, particularly infants.

Dohan¹ made an excellent review of the literature on gangrene of the extremities in the new-born, and much of the information included in the accompanying table was compiled from the data which he gathered. Heller and Alvari² likewise presented an admirable review of gangrene of the extremities in newly born babies. Martin and Shore³ studied 4 patients, ranging in age from 4 to 14 years, with gangrene of the extremities. These writers particularly emphasized the role of severe sepsis in production of arterial thrombosis in children. Their discussion centered principally on lesions of older subjects and had little to do with infants. Von Khautz⁴ collected a group of 50